Results 101 to 110 of about 2,731,657 (292)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Directed search with stochastic resetting and multiple objectives

Journal of Physics Communications
In the present study, the dynamic growth and contraction behavior of nucleated cells in source cells can be simulated as a mathematical process that combines elements such as directed search, stochastic resetting and delay.
Yan Xu, Yiwen Shang
doaj   +1 more source

Bacterial Foraging Optimization –Genetic Algorithm for Multiple Sequence Alignment with Multi-Objectives

Scientific Reports, 2017
This research work focus on the multiple sequence alignment, as developing an exact multiple sequence alignment for different protein sequences is a difficult computational task.
P. Manikandan, D. Ramyachitra
doaj   +1 more source

Analyzing fast and slow: Combining traditional and rapid qualitative analysis to meet multiple objectives of a complex transnational study. [PDF]

Front Sociol, 2023
Suchman L, Omoluabi E, Kramer J, Vallin J, Sedlander E, Gitome S, Wekesa P, Kwena Z, Granovsky R, Kayego A, Kaudha B, Atuyambe L, Amongin D, Alitubeera P, Tijani A, Okoli C, Jegede A, Kamanga M, Nyando M, Ndunyu L, Holt K, ICAN Research Consortium.   +21 more
europepmc   +1 more source

Aid Effectiveness and Selectivity: Integrating Multiple Objectives into Aid Allocations [PDF]

aid, growth, policy, selectivity, poverty reduction, post-conflict, democracy, political stability, economic ...
McGillivray, Mark
core  

Multiobjective Robust Control with HIFOO 2.0

, 2009
Multiobjective control design is known to be a difficult problem both in theory and practice. Our approach is to search for locally optimal solutions of a nonsmooth optimization problem that is built to incorporate minimization objectives and constraints
Gumussoy, Suat, Henrion, Didier, Millstone, Marc, Overton, Michael L.   +3 more
core   +6 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Evaluating the effectiveness of palm oil certification in delivering multiple sustainability objectives

Environmental Research Letters, 2018
Industrial oil palm plantations in South East Asia have caused significant biodiversity losses and perverse social outcomes. To address concerns over plantation practices and in an attempt to improve sustainability through market mechanisms, civil ...
Courtney L Morgans, Erik Meijaard, Truly Santika, Elizabeth Law, Sugeng Budiharta, Marc Ancrenaz, Kerrie A Wilson   +6 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

A Note on Solvability Conditions for Multiple Objectives Linear Programming (MOLP) Problems

Journal of Algorithms & Computational Technology, 2011
This paper investigates the advantages of using a simple linear programming problem with one unknown to show that whether the given multiple objectives linear programming (MOLP) problems is solvable or not.
S.F. Tantawy
doaj   +1 more source