Results 191 to 200 of about 6,285,374 (227)

A New Classification System for Forearm Deformities Caused by Hereditary Multiple Osteochondromas.

Journal of Hand Surgery-American Volume
PURPOSE The objective of this study was to evaluate the Masada and Jo classifications for clinical use in patients with forearm deformity caused by hereditary multiple osteochondroma and propose a new classification system that is all-inclusive and can ...
C. X. Chan, Jun Song, Chin Yee Woo, K. Lam, M. Puhaindran, B. Ning, Hoi Po James Hui   +6 more
semanticscholar   +1 more source

Forearm Giant Osteochondromas in a Young Patient With Multiple Hereditary Exostoses: A Case Report

Cureus
Multiple hereditary exostoses (MHE) is a rare skeletal disorder inherited as an autosomal dominant disorder. It is characterized by widespread multiple osteochondromas that grow near bone growth plates, leading to pain and deformities that significantly ...
S. R. Sulaiman, Hossam M Ismail, S. A. Al-Zubaidi, Osama F Almaghthawi, Ahmed M Alrehaili, Rayan Alarabi   +5 more
semanticscholar   +1 more source

Operations for forearm deformity caused by multiple osteochondromas

The Journal of Bone and Joint Surgery. British volume, 1989
We reviewed 36 cases of forearm deformity caused by multiple osteochondromas in 30 patients and classified them into three types: Type I showed a combination of ulnar shortening and bowing of the radius secondary to osteochondromas of the distal ulna (22 forearms).
K, Masada, Y, Tsuyuguchi, H, Kawai, H, Kawabata, K, Noguchi, K, Ono   +5 more
openaire   +2 more sources

Multiple occurrence of osteochondromas in dysplasia epiphysealis hemimelica

Archives of Orthopaedic and Trauma Surgery, 2000
Dysplasia epiphysealis hemimelica was defined by Trevor (1950) as a rare congenital growth disorder of the tarsus and of the epiphysis of the long bone. In this report, a rare case of dysplasia epiphysealis hemimelica associated with multiple extraskeletal osteochondromas is presented.
M, Takagi, Y, Kiyoshige, A, Ishikawa, T, Ogino   +3 more
openaire   +2 more sources

The neoplastic pathogenesis of solitary and multiple osteochondromas

The Journal of Pathology, 1999
Many theories of osteochondroma pathogenesis have been advanced. Genetic research into the inherited multiple form, hereditary multiple exostoses, has revealed a new family of tumour suppressor genes denoted EXT. Patterns of EXT gene mutation in hereditary multiple exostoses, in solitary and multiple osteochondromas, and in chondrosarcoma are analogous
D E, Porter, A H, Simpson
openaire   +2 more sources

Mutational spectrum and clinical signatures in 114 families with hereditary multiple osteochondromas: insights into molecular properties of selected exostosin variants.

Human Molecular Genetics, 2019
Hereditary multiple osteochondromas (HMO) is a rare autosomal dominant skeletal disorder, caused by heterozygous variants in either EXT1 or EXT2, which encode proteins involved in the biogenesis of heparan sulphate.
C. Fusco, G. Nardella, R. Fischetto, M. Copetti, A. Petracca, Francesca Annunziata, Bartolomeo Augello, Maria Cecilia D’Asdia, Simona Petrucci, T. Mattina, Annalisa Rella, M. Cassina, Mario Bengala, T. Biagini, Francesco Andrea Causio, C. Caldarini, F. Brancati, A. De Luca, V. Guarnieri, L. Micale, L. D'agruma, M. Castori   +21 more
semanticscholar   +1 more source

Short-term outcomes of gradual ulnar lengthening in multiple hereditary osteochondromas of the forearm with monolateral external fixator.

Journal of pediatric orthopedics. Part B
Hereditary multiple exostoses is an autosomal dominant genetic condition primarily affecting long bones. Forearm deformities, including wrist ulnar deviation, ulnar shortening, radial or ulnar bowing, and radial head dislocation, are common ...
S. Moein, Javad Dehghani, Reza Fereidooni, Mohammad Hadi Gerami, Asal Seifaei, Seyyed Hamidreza Ayatizadeh   +5 more
semanticscholar   +1 more source

RATE OF SPINAL OSTEOCHONDROMAS DIAGNOSED VIA ADVANCED IMAGING IN PAEDIATRIC PATIENTS WITH HEREDITARY MULTIPLE OSTEOCHONDROMAS: A SYSTEMATIC REVIEW AND META-ANALYSIS

Orthopaedic Proceedings
Hereditary multiple osteochondromas (HMO) is a common paediatric condition defined by the presence of multiple cartilage-capped bony lesions. Spinal osteochondromas affect up to 68% of HMO patients.1 Although most are asymptomatic, cord-encroaching ...
J. Legler, L. Benaroch, A. A. Pirshahid, O. Serhan, D. Bartley, T-P. Carey   +5 more
semanticscholar   +1 more source

Is total-body MRI useful as a screening tool to rule out malignant progression in patients with multiple osteochondromas? Results in a single-center cohort of 319 adult patients

Skeletal Radiology, 2023
H. Woude, M. Flipsen, C. Welsink, Arnard L. Zwan, S. Ham   +4 more
semanticscholar   +1 more source

Hereditary Multiple Osteochondromas

Consultant, 2021
Zackary Funk, Priya Sharma, Carolyn Carter   +2 more
openaire   +1 more source