Results 51 to 60 of about 1,671 (162)

The Pathophysiological Functions of Heparanases: From Evolution, Structural and Tissue‐Specific Perspectives

open access: yesThe FASEB Journal, Volume 39, Issue 17, 15 September 2025.
Heparanase 1 (HPSE1) and Heparanase 2 (HPSE2) exhibit opposing expression patterns and functions in pathological contexts, such as cancer. Here, we describe their specific expression in immune cells and their implications in skin diseases. Although they are structurally similar and considered to be ‘cousins’, we found no common ancestor and that HPSE2 ...
Elham Vahdatahar   +12 more
wiley   +1 more source

Chondrosarcoma in Metachondromatosis: A Rare Case Report

open access: yesActa Medica Iranica, 2018
Metachondromatosis which was first described in 1971 by Maroteaux is a rare genetic disease consisting of osteochondromas and enchondromas, caused by loss of function of the PTPN11 gene.
Khodamorad Jamshidi   +2 more
doaj  

Hereditary multiple exostoses: an educational review

open access: yesInsights into Imaging
Hereditary multiple exostoses (HME), an autosomal dominant disorder with an incidence of 1:50,000 to 1:100,000, is characterised by the formation of multiple osteochondromas arising from the metaphyses of long and flat bones.
Alvaro Rueda-de-Eusebio   +5 more
doaj   +1 more source

A 40-Year-Old Male Presenting with Hereditary Multiple Exostosis: Management and Considerations

open access: yesCase Reports in Orthopedics, 2019
Hereditary multiple exostosis is a rare condition in which numerous benign osteochondromas form throughout the body, typically in areas of high bone turnover such as the metaphyseal plates of long bones.
Matthew Wells, Zackary Birchard
doaj   +1 more source

Teleangiectatic Osteosarcoma Treated by Surgery and Chemotherapy: A Report of 223 Affected Patients From the Cooperative Osteosarcoma Study Group (COSS)

open access: yesCancer Medicine, Volume 14, Issue 17, September 2025.
ABSTRACT Purpose Teleangiectatic osteosarcoma is a histologic subtype of osteosarcoma that can mimic aneurysmal bone cysts and has so far been incompletely characterized. Patients and Methods We used the database of the Cooperative Osteosarcoma Study Group COSS (patient‐registration 1980–2019) to better understand this rare histologic variant.
Stefan S. Bielack   +17 more
wiley   +1 more source

Pain in patients with multiple inherited osteochondromas: Incidence and potential prognostic factors. A retrospective cohort study

open access: yesJournal of Bone Oncology
Purpose: the purpose of this study was to describe the baseline characteristics, presenting phenotype and treatment interventions for patients diagnosed with multiple osteochondromas who presented with severe pain symptoms.
Morena Tremosini   +8 more
doaj   +1 more source

Multiple exostoses and an osteochondroma in a Pliocene canid from Langebaanweg ‘E’ Quarry (South Africa)

open access: yesJournal of Anatomy, Volume 247, Issue 3-4, Page 856-868, September/October 2025.
Overview of XS of pathological radius. Using anatomical descriptions, CT scanning and bone histology, we investigate several skeletal overgrowths of bone (exostoses) in the skeleton of a jackal‐like canid from the world famous Langebaanweg, a Mio‐Pliocene locality in South Africa.
Anusuya Chinsamy, Alberto Valenciano
wiley   +1 more source

Hemothorax caused by costal exostosis injuring diaphragm: a case report and literature review

open access: yesJournal of Cardiothoracic Surgery, 2022
Background Osteochondromas, also known as exostoses, are the most common benign tumors of bone and can be classified into isolated and multiple osteochondromas.
Ruonan Pan   +4 more
doaj   +1 more source

Novel report of an osteogenic tumor in a late Jurassic Mamenchisaurid from Thailand

open access: yesJournal of Anatomy, Volume 247, Issue 3-4, Page 699-711, September/October 2025.
Here we describe a pathology in an ulna of a Late Jurassic mamenchisaurid from Thailand. We use anatomical descriptions, CT scanning, and bone histology to identify the pathology as an osteogenic tumor. Abstract Here we report on an osseous abnormality and multiple fractures in an ulna of a subadult basal Eusauropod (Mamenchisauridae) from the Late ...
Siripat Kaikaew   +2 more
wiley   +1 more source

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