Integrating Surgery and Ablative Therapies for the Management of Multiple Primary Lung Cancer: A Systematic Review. [PDF]
Dong Z +6 more
europepmc +1 more source
The association of self-perceived changes due to COVID-19 with mental and physical health among adult primary care patients with multiple chronic conditions: A US-based longitudinal study [PDF]
Levi N. Bonnell +4 more
openalex +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Genomic classification of intrapulmonary metastasis and multiple primary lung cancer. [PDF]
Won J +5 more
europepmc +1 more source
Correction to: Complex multiple risk intervention to promote healthy behaviours in people between 45 to 75 years attended in primary health care (EIRA study): study protocol for a hybrid trial [PDF]
Edurne Zabaleta‐del‐Olmo +26 more
openalex +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Association of Inherited Genetic Variants with Multiple Primary Melanoma. [PDF]
Gibbs DC +22 more
europepmc +1 more source
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
A CT-based deep learning approach to differentiate multiple primary lung cancers, metastases, and benign nodules. [PDF]
Liufu Y +4 more
europepmc +1 more source

