Results 171 to 180 of about 1,293,842 (319)

EP1.12-14 Multiple Primary Malignant Neoplasms in Patients with Small Cell Lung Cancer. The Experience of Our Center [PDF]

, 2019
Michael Vaslamatzis, Theodoros Tegos, Nektarios Alevizopoulos, M. Pavlakis, Katerina Karagiorgou, E. Patila, Katerina Gioti, Dimitrios Exarchos, Charalambos Zisis   +8 more
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Collision tumor: a parathyroid adenoma unveiling subclinical widespread breast carcinoma: a case report. [PDF]

J Med Case Rep
Yacoub S, Bil Hadj Miled H, Mokni W, Elfkih H, Belakhder M, Mokni M.   +5 more
europepmc   +1 more source

MULTIPLE PRIMARY MALIGNANT NEOPLASMS- AN INTERESTING CASE REPORT

, 2018
Chandni Krishnani, Tandon R. K, Goswami S. S, Payal Desai   +3 more
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Subsequent primary and secondary neoplasms in childhood cancer survivors. [PDF]

Pol J Radiol
Bekiesińska-Figatowska M, Bilska K, Szkudlińska-Pawlak S, Klepacka T, Raciborska A, Koch I, Michalak E.   +6 more
europepmc   +1 more source

Multiple Primary Malignant Neoplasms in Gynaecology

International Journal of Clinical Practice, 1976
B, Rajhvajn, A, Kurjak, J M, Beazley
openaire   +2 more sources

A patient with multiple primary malignant neoplasms with high variant allele frequencies of RB1, TP53, and TERT [PDF]

Mingyang Ma, Kun Shang, Jiewei Wang, Xiaojing Teng, Peng Li, Jing Wang   +5 more
openalex   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source