Results 231 to 240 of about 1,081,535 (384)

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Primary central nervous system tumors in patients with multiple sclerosis. [PDF]

BMC Neurol
Sabouri M, Etemadifar M, Dehghani Firoozabadi F, Sindarreh S, Akhavan-Sigari A.   +4 more
europepmc   +1 more source

Endoscopic diagnosis and treatment of primary multiple noninvasive malignant neoplasms of the stomach: clinical case

Д. Г. Сухин, С. С. Пирогов, V. I. Ryabtseva, Irina V. Kuprina, O. К. Yutsevich, I. B. Perfiliev, G. F. Minibaeva, А. С. Водолеев, Л. В. Телегина, А. Д. Каприн   +9 more
openalex   +2 more sources

Multiple primary malignant neoplasms series: Recent results in cancer research

, 1979
Joop W. Barents
openalex   +1 more source

Multiple malignant primary neoplasms in patients with gastric neoplasms in the health district of León [PDF]

, 2006
Alberto Muela Molinero, Francisco Jorquera, Toru Arino, R. Malagón Rojo, V. Espinel Díez, Beatriz Ballesteros del Río, J.L. Olcoz Goñi, J.A. Santos Calderón   +7 more
openalex   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Characteristic Findings of Honeycomb-Like Structures in Patients With Chronic Coronary Syndrome Complicated With Myeloproliferative Neoplasms. [PDF]

JACC Case Rep
Shimosato H, Usui E, Sayama K, Kanaji Y, Hada M, Nagamine T, Ueno H, Setoguchi M, Watanabe T, Kakuta T.   +9 more
europepmc   +1 more source

Detection of hypoxia-inducible factor in multiple primary malignant neoplasms of the kidney and prostate gland

Artyom M. Mylnikov, Alla B. Bucharskaya, Д. А. Мудрак, Galina N. Maslyakova   +3 more
openalex   +1 more source

MULTIPLE PRIMARY MALIGNANT NEOPLASMS ASSOCIATED WITH GENITO-URINARY ORGANS

, 1980
Hideo Kamada, Tsuyoshi Shiraga
openalex   +2 more sources

Germline variants in CDKN2A wild‐type melanoma prone families

Molecular Oncology, Volume 19, Issue 5, Page 1493-1507, May 2025.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen, Marie Loeng, Amalie Lund Holth, Per E. Lønning, Jürgen Geisler, Stian Knappskog   +5 more
wiley   +1 more source