Results 271 to 280 of about 1,081,535 (384)

Revealing neuroendocrine transformation in gynecological cancers through genomic analysis. [PDF]

NPJ Precis Oncol
Oluloro A, Wells DL, Childers CK, Luu T, Eaton KD, Urban RR, Konnick EQ, Paulson VA, Banda K.   +8 more
europepmc   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Second primary cancers among males with a first primary prostate cancer: a population-based study in Northern Portugal. [PDF]

Clin Exp Med
Taveira-Barbosa J, Morais S, Garcia T, Bento MJ, Lunet N.   +4 more
europepmc   +1 more source

A rare case of eight multiple primary malignant neoplasms in a female patient: A case report and review of the literature

, 2014
Jiemin Zhao, Yan Tan, Yugang Wu, Wei Zhao, Jun Wu, Mei Ji, Liangrong Shi, Jingting Jiang, Changping Wu   +8 more
openalex   +2 more sources

NPC1 promotes the progression of hepatocellular carcinoma by mediating the accumulation of neutrophils into the tumor microenvironment

FEBS Open Bio, Volume 15, Issue 4, Page 661-673, April 2025.
Compared to normal tissues, NPC1 expression is significantly elevated in hepatocellular carcinoma tissues. Our findings indicate that NPC1 plays a key role in regulating neutrophil recruitment within the tumor, which is a critical factor in the progression of hepatocellular carcinoma and is closely linked to poor patient outcomes.
Songhai Yang, Jiangming Chen, Kun Xie, Fubao Liu   +3 more
wiley   +1 more source

Therapy related acute myeloid leukemia secondary to CAR-T therapy in refractory/relapsed multiple myeloma patient showing poor prognosis. [PDF]

Ann Hematol
An R, Bao W, Yan Z, Sun H, Xu X, Zhang S.   +5 more
europepmc   +1 more source

Dexmedetomidine suppresses glucose‐stimulated insulin secretion in pancreatic β‐cells

FEBS Open Bio, Volume 15, Issue 4, Page 634-646, April 2025.
Dexmedetomidine decreases insulin release and affects glucose metabolism; however, the specific mechanism remains largely unknown. This study shows clinically relevant doses of dexmedetomidine suppressed glucose‐stimulated insulin secretion. There was no significant difference in oxygen consumption rate, intracellular ATP levels, or caspase‐3/7 ...
Munenori Kusunoki, Kiichi Hirota, Tomohiro Shoji, Takeo Uba, Yoshiyuki Matsuo, Mikio Hayashi   +5 more
wiley   +1 more source

The Role of Megakaryocyte Assessment in Bone Marrow Cytology. [PDF]

J Clin Med
Błocka-Gumowska M, Hus I, Szymczyk A.
europepmc   +1 more source

CDK5 interacts with MST2 and modulates the Hippo signalling pathway

FEBS Open Bio, Volume 15, Issue 4, Page 647-660, April 2025.
By using a yeast‐two‐hybrid system, immune precipitation and a proteomics approach, we identify a novel interaction between CDK5 and MST2, which modulates the mechano‐sensitive Hippo signalling pathway in a liver tumour cell line. MST2 (STK3) is a major upstream kinase in the Hippo signalling pathway, an evolutionary conserved pathway in regulation of ...
Mehak Passi, Jan B. Stöckl, Thomas Fröhlich, Simone Moser, Angelika M. Vollmar, Stefan Zahler   +5 more
wiley   +1 more source

Solitary intradural extramedullary recurrence of testicular diffuse large B-cell lymphoma mimicking a schwannoma: illustrative case. [PDF]

J Neurosurg Case Lessons
Knox M, Starasoler L, Herschman Y.
europepmc   +1 more source