Results 51 to 60 of about 3,875,320 (272)

Study on the cause of short-term rise of water level in Bengbu monitoring center well

open access: yes地震科学进展, 2023
Based on the previous study on the long-term rise of water level in Bengbu monitoring center well, we analyze 59 short-time rises of the water level in Bengbu monitoring center well from 2017 to 2020. By selecting rainfall parameters in different periods
Xiaolei Shi   +5 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Sociodemographic and Digital Education Factors Are Associated to General Health, Coping Strategies, and Academic Outcomes of Undergraduate Students during the Post-Pandemic Period

open access: yesEuropean Journal of Investigation in Health, Psychology and Education, 2022
The COVID-19 pandemic suddenly and forever changed the lives of many undergraduate students around the globe, forcing them to switch to online learning while undergoing social confinement within their homes. It is now well-established that this prolonged
Luigi Tinella   +5 more
doaj   +1 more source

A Multiple Regression Analysis of Personality’s Impact on Actuarial Exam Performance [PDF]

open access: yes, 2011
Existing literature indicates that there is some connection between personality and both academic and work-related performance. The author\u27s intent for the research described herein is to explore this connection for students majoring in actuarial ...
Ciaffone, Matthew
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

The Formation Of Green Buying Strategy On The Scope Of Consumer Decision Making Behavior

open access: yesOnline Academic Journal of Information Technology, 2013
As the natural resources are becoming scarce and the concept of environmentalism is on the rise, green buying behavior has increased the attention of many academicians and practitioners as an emerging strategy.
M. Yaman Oztek, Ozgur Cengel
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Multiple Linear Regression Applications in Real Estate Pricing [PDF]

open access: yes, 2016
In this paper, we attempt to predict the price of a real estate individual homes sold in North West Indiana based on the individual homes sold in 2014. The data/information is collected from realtor.com.
Hughes, Zachariah   +3 more
core   +1 more source

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