Results 71 to 80 of about 3,661,943 (288)

The Effect Analysis of Motivation, Competence and Organizational Culture on Employees Performance of Jakarta Social Department [PDF]

open access: yes, 2019
All this time, government institutions are still overshadowed by stigma, the poor performance of civil servants. Therefore, this research was conducted to analyze the influence of performance factors, including motivation, competence and organizational ...
Finatariani, E. (Endah)
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Application of Multiple Regression Analysis in modeling the role of the hotel industry in a country's economy [PDF]

open access: yesJournal of Economic and Social Development (Varaždin), 2022
The aim of this paper is to present the relationship between independent variables that represent one of the indicators of hotel operations and their importance for the country's economic development as measured by gross domestic product in the ...
Buljat Maja   +2 more
doaj  

Multiple regression analysis of big weather-based outage data [PDF]

open access: yes, 2016
poster abstractBig data analytics has been recently used in various fields in order help derive data-driven knowledge. In this study, we use statistical methods and data analytics techniques to investigate the potential relationship between weather ...
Ren, Boyang
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Estimators of the multiple correlation coefficient: local robustness and confidence intervals. [PDF]

open access: yes
Many robust regression estimators are defined by minimizing a measure of spread of the residuals. An accompanying R-2-measure, or multiple correlation coefficient, is then easily obtained.
Croux, Christophe, Dehon, C
core  

Multifactorial analysis of human blood cell responses to clinical total body irradiation [PDF]

open access: yes, 1972
Multiple regression analysis techniques are used to study the effects of therapeutic radiation exposure, number of fractions, and time on such quantal responses as tumor control and skin injury.
Lushbaugh, C. C.   +2 more
core   +1 more source

An approach for jointly modeling multivariate longitudinal measurements and discrete time-to-event data

open access: yes, 2010
In many medical studies, patients are followed longitudinally and interest is on assessing the relationship between longitudinal measurements and time to an event.
Albert, Paul S., Shih, Joanna H.
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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