Results 71 to 80 of about 512,629 (287)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Risk factors for liver Cancer in HIV endemic areas of Western Kenya

open access: yesInfectious Agents and Cancer, 2018
Background Hepatocellular carcinoma (HCC) is a malignant cancer of the liver and a leading cause of cancer-related mortality worldwide. Human immunodeficiency virus (HIV) has not been known to have a direct causal relationship with HCC despite ...
Amos Otedo   +4 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Estimation of multiple-regime regressions with least absolutes deviation [PDF]

open access: yes
This paper considers least absolute deviations estimation of a regression model with multiple change points occurring at unknown times. Some asymptotic results, including rates of convergence and asymptotic distributions, for the estimated change points ...
Jushan, Bai
core   +1 more source

Multiple logistic regressions: controlling factors in applications to soil class prediction. [PDF]

open access: yes, 2014
Métodos mais eficazes para determinação do padrão de distribuição de classes de solo na paisagem precisam ser avaliados visando suprir a demanda por mapas de solo em escalas regional e global.
CATEN, A. Ten   +3 more
core  

Forecasting in the presence of recent structural change [PDF]

open access: yes, 2011
We examine how to forecast after a recent break. We consider monitoring for change and then combining forecasts from models that do and do not use data before the change; and robust methods, namely rolling regressions, forecast averaging over different ...
Eklund, J., Kapetanios, G., Price, S.
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Assessment of postharvest loss along potato value chain: the case of Sheka Zone, southwest Ethiopia

open access: yesAgriculture & Food Security, 2018
Background Ethiopia has possibly the highest potential for potato production than any country in Africa. Postharvest loss (20–25%) is one of the major problems in the potato production.
Benyam Tadesse   +2 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Analysis of Gamasyab River Flood by Multi-Regression Method [PDF]

open access: yesجغرافیا و پایداری محیط, 2013
Estimating flood hit areas with limited or no statistical significant issues in the design of water structures and water resources management is a very important topic especially in arid and semi-arid areas.
Nabe Khazaei   +2 more
doaj  

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