Results 71 to 80 of about 669,844 (267)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Multiple Idiopathic Apical Root Resorption: a Case Report

open access: yesFrontiers in Dentistry, 2010
The aim of this case report was to present a case of multiple idiopathic apical root resorption which is a rare condition in a 17-year-old adult male. External root resorption of the permanent teeth is a multifactorial process.
L. Khojastepour   +2 more
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Multiple root coverage with subepithelial connective tissue graft, 8-year follow-up: A case report

open access: yesMexican Journal of Medical Research ICSA
Some of the challenges of root coverage with connective tissue graft are donor site morbidity and patient discomfort from the surgical procedure, as well as poor patient cooperation in correcting and controlling precipitating and predisposing factors of ...
Iriana Y. Angeles Espinosa
doaj   +1 more source

On Derivative Free Multiple-Root Finders with Optimal Fourth Order Convergence

open access: yesMathematics, 2020
A number of optimal order multiple root techniques that require derivative evaluations in the formulas have been proposed in literature. However, derivative-free optimal techniques for multiple roots are seldom obtained.
Janak Raj Sharma   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Особенности эндодонтического лечения премоляров со сложной системой корневых каналов. Часть II

open access: yesЭндодонтия Today, 2020
One of the source of the bad quality endodontic treatment leading to the development of the chronical periapical lesions may be missed and unfilled root channel. Premolars are teeth with multiple root canal system.

doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Treatment of multiple gingival recessions adopting modified tunnel subepithelial connective tissue graft technique

open access: yesIndian Journal of Dental Research, 2014
Gingival recession related to periodontal disease or developmental problems can result in root sensitivity, root caries, and esthetically unacceptable root exposures. In the past, multiple surgical procedures have been proposed to obtain root coverage on
Jagmohan Singh, Vipin Bharti
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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