Results 31 to 40 of about 1,882,584 (263)
Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall +2 more
wiley +1 more source
Background Large nucleotide sequence datasets are becoming increasingly common objects of comparison. Complete bacterial genomes are reported almost everyday. This creates challenges for developing new multiple sequence alignment methods.
Kryukov Kirill, Saitou Naruya
doaj +1 more source
The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo +5 more
wiley +1 more source
Health Literacy, Self‐Efficacy and Knowledge of Sickle Cell Disease Among Caregivers
ABSTRACT Background Sickle cell disease (SCD) is a hereditary blood disorder in which abnormal haemoglobin leads to severe anaemia, painful crises and organ failure. Caregivers’ health literacy (HL) – their ability to assess, understand and apply information, and interact with healthcare professionals – is crucial for managing children with SCD, yet ...
Melanie Bruinooge +6 more
wiley +1 more source
A Multiple-Scale Space–Time Collocation Trefftz Method for Two-Dimensional Wave Equations
This paper presents a semi-analytical, mesh-free space–time Collocation Trefftz Method (SCTM) for solving two-dimensional (2D) wave equations. Given prescribed initial and boundary data, collocation points are placed on the space–time (ST) boundary ...
Li-Dan Hong +5 more
doaj +1 more source
Off-Grid Channel Estimation for Extremely Large Scale MIMO Based on Simplex Method [PDF]
This paper proposes an off-grid near-field channel estimation algorithm based on the simplex method to address the estimation error problem of sampling points on the grid caused by grid channel estimation using polar-domain sparsity in eXtremely Large ...
HE Tianyi, CAO Haiyan, JI Yangrui, XU Fangmin
doaj +1 more source
Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte +5 more
wiley +1 more source
This paper investigates the dynamic response of rectangular prestressed membrane subjected to concentrated impact load based on multiple scale perturbation method.
Z. L. Zheng, C. Y. Liu, D. Li, T. Zhang
doaj +1 more source
ABSTRACT Background Pediatric bone sarcoma patients and survivors may experience psychosocial challenges related to childhood cancer after their intensive, body‐altering treatment. This cross‐sectional study aimed to evaluate generic and survivor‐specific psychosocial outcomes in a national cohort of pediatric bone sarcoma patients and survivors, and ...
Hinke van der Hoek +14 more
wiley +1 more source
Method of multiple scales in scalar field cosmology
Abstract In this work, the method of multiple scales is applied to analysis of cosmological dynamics. The method is used to construct solutions to the dynamic equations of the Universe filled with a scalar field in the Friedman-Robertson-Walker metric.
V M Zhuravlev, S V Chervon
openaire +1 more source

