Results 141 to 150 of about 6,495,609 (392)

Clonally expanded B cells in multiple sclerosis bind EBV EBNA1 and GlialCAM

open access: yesNature, 2022
Tobias V. Lanz   +29 more
semanticscholar   +1 more source

Multiple sclerosis: clinical aspects

open access: yesCurrent Opinion in Neurology, 2018
Purpose of review Multiple sclerosis is a chronic, predominantly immune-mediated disease of the central nervous system, and one of the most common causes of neurological disability in young adults globally.
Jiwon Oh   +2 more
semanticscholar   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan   +22 more
wiley   +1 more source

Relapsing-remitting multiple sclerosis: advances in disease-modifying therapies [PDF]

open access: yes, 2015
Multiple sclerosis is a demyelinating disease affecting the central nervous system. It is the most prevalent disabling neurological condition among young adults, with onset typically between 20 and 40 years of age. Infiltrating immune cells and microglia
Kay, Kathleen Alexandra
core   +1 more source

Group sequential designs for negative binomial outcomes

open access: yes, 2018
Count data and recurrent events in clinical trials, such as the number of lesions in magnetic resonance imaging in multiple sclerosis, the number of relapses in multiple sclerosis, the number of hospitalizations in heart failure, and the number of ...
Friede, Tim   +3 more
core   +1 more source

Vitamin D Status During Pregnancy and Risk of Multiple Sclerosis in Offspring of Women in the Finnish Maternity Cohort [PDF]

open access: bronze, 2016
Kassandra L. Munger   +5 more
openalex   +1 more source

Cognition in multiple sclerosis

open access: yesNeurology, 2018
Cognitive decline is recognized as a prevalent and debilitating symptom of multiple sclerosis (MS), especially deficits in episodic memory and processing speed.
J. Sumowski   +11 more
semanticscholar   +1 more source

Network Localization of Fatigue in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo   +12 more
wiley   +1 more source

Recommendations for cognitive screening and management in multiple sclerosis care

open access: yesMultiple Sclerosis, 2018
Purpose: To promote understanding of cognitive impairment in multiple sclerosis (MS), recommend optimal screening, monitoring, and treatment strategies, and address barriers to optimal management.
R. Kalb   +15 more
semanticscholar   +1 more source

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