Results 241 to 250 of about 755,873 (344)

Multiple Sclerosis [PDF]

, 1960
H. Miller, A Ridley, Kurt Schapira
openalex   +1 more source

From Bench to Bedside: Emerging Paradigms in CAR‐T Cell Therapy for Solid Malignancies

Advanced Science, EarlyView.
This review discusses emerging paradigms in CAR‐T cell therapy for solid tumors, emphasizing strategies to overcome therapeutic barriers through synthetic biology, immune engineering, and combinatorial approaches. It highlights advancements in logic gating, modulation of the immune microenvironment, and innovative cell designs, providing valuable ...
Yang Chen, Ran Ren, Lirong Yan, Yu Zhou, Ruokai Sun, Huicong Song, Hongfei Yan, Yongsheng Li   +7 more
wiley   +1 more source

A Phenomenological Understanding of Aging "Well" With Multiple Sclerosis. [PDF]

Gerontologist
Richardson EV, Motl RW.
europepmc   +1 more source

Metabolic Programming Drives Protective and Inflammatory Monocyte Fates in Viral Encephalitis

Advanced Science, EarlyView.
Bone marrow monocytes infiltrate the West Nile virus‐infected brain and differentiate into HIF1‐α⁺ monocyte‐derived cells (MCs) that diverge into protective, antigen‐presenting or inflammatory, iNOS⁺ MCs with distinct metabolic programs and functions.
Claire L. Wishart, Alanna G. Spiteri, Jian Tan, Laurence Macia, Nicholas J. C. King   +4 more
wiley   +1 more source

Bowel Dysfunctions in Young Adults with Multiple Sclerosis: A Retrospective Study. [PDF]

Med Sci (Basel)
Sessa E, Bonanno L, Susinna C, Ivaldi D, Triolo G, Lombardo R, D'Aleo G, Rifici C, Lo Buono V.   +8 more
europepmc   +1 more source

Variations in Innate Immune Cell Subtypes Correlate with Epigenetic Clocks, Inflammaging and Health Outcomes

Advanced Science, EarlyView.
This study uses a high‐resolution DNA methylation reference panel for 19 immune cell‐types, as well as transcriptomic, metabolomic, and large population cohort data to show that age‐related epigenetic heterogeneity within monocytes correlates with inflammaging, biological age, and all‐causemortality, and does so more strongly than existing monocyte ...
Xiaolong Guo, Josephine A. Robertson, Andrea Aparicio, Kirsten Seale, Qingwen Chen, Anne Richmond, Zhaozhen Du, Mahnoor Sulaiman, Shijie C Zheng, Esteban Ballestar, Charlotte AM Cecil, Bastiaan T Heijmans, Steve Horvath, Varun B. Dwaraka, Jessica Lasky‐Su, Ryan Smith, Riccardo E. Marioni, Andrew E Teschendorff   +17 more
wiley   +1 more source

Tendinopathy: The Interplay between Mechanical Stress, Inflammation, and Vascularity

Advanced Science, EarlyView.
This review explores the complex and self‐reinforcing cycle of mechanical stress, inflammation, and altered vascularity in tendinopathy—a common, painful tendon disorder. It integrates current findings on cellular, molecular, and biomechanical mechanisms, highlighting how mechanical overload, inflammatory signals, and abnormal blood vessel behavior ...
Renate Gehwolf, Herbert Tempfer, Nevra Pelin Cesur, Andrea Wagner, Andreas Traweger, Christine Lehner   +5 more
wiley   +1 more source

NamiRNA‐Enhancer Network: The Changing Era Challenge and Chance of miRNA

Advanced Science, EarlyView.
MiRNAs (miRNAs) regulate diverse biological processes across species. Unlike canonical miRNA‐mediated gene repression, Nuclear Activating miRNAs (NamiRNAs) can efficiently upregulate gene expression by targeting enhancers. This review systematically summarizes recent advances in NamiRNA research, elucidates the theory of NamiRNA‐Enhancer‐mediated Gene ...
Lu Chen, Ying Liang, Hongyan Wei, Mengxing Liu, Jin Wu, Wei Li, Wenxuan Li, Yuxiao Jin, Yinshan Li, Wei Zhao, Min Xiao, Kaicheng Zhou, Shuai Yang, Wenqiang Yu   +13 more
wiley   +1 more source

Unraveling Microstructural and Macrostructural Brain Age Dynamics in Multiple Sclerosis. [PDF]

Neurol Neuroimmunol Neuroinflamm
Chen X, Lu PJ, Ocampo-Pineda M, Cagol A, Schaedelin SA, Ruberte E, Weigel M, Spagnolo F, Benkert P, Lieb JM, Leppert D, Yaldizli Ö, Oechtering J, D'Souza M, Fischer-Barnicol B, Derfuss TJ, Ekerdt C, Menks WM, Chan KS, Zwiers M, Chan A, Hoepner R, Wagner F, Pot C, Du Pasquier RA, Finkener S, Diepers M, Bridel C, Lalive PH, Uginet M, Gobbi C, Zecca C, Pravatà E, Disanto G, Roth P, Vehoff J, Mueller S, Chan-Hi Kim O, Kappos L, Kuhle J, Melie-Garcia L, Marques JP, Granziera C.   +42 more
europepmc   +1 more source

Geographic and Climatic Aspects of Multiple Sclerosis

, 1964
Leonard T. Kurland, Dwayne Reed
openalex   +2 more sources