Results 261 to 270 of about 752,420 (346)

Oral Manifestations of Multiple Sclerosis: A Systematic Review. [PDF]

J Clin Med
García-Rios P, Rodríguez-Lozano FJ, Pecci-Lloret MR.   +2 more
europepmc   +1 more source

AGE COHORT ANALYSIS: A METHOD OF ESTIMATING FREQUENCY CHANGES IN MULTIPLE SCLEROSIS

, 1968
Aaron Antonovsky, Milton Alter, Uri Leibowitz   +2 more
openalex   +1 more source

Establishment of a humanized SCA2 mouse model carrying a CAA disruption preventing CAG repeat expansion in pathogenic genes

Animal Models and Experimental Medicine, EarlyView.
In this study, we established a mouse model in which CAG repeats do not undergo microsatellite instability (MSI) across generations. A humanized ATXN2 cDNA with four CAA interruptions within 73 CAG expansions was inserted into the Rosa26 locus of C57BL/6J mice. At the same time, a 23 CAG control mouse model was also generated.
Yao Zhang, Yufei Li, Lin Zhang, Zhaoqing Li, Keqin Lin, Kai Huang, Zhaoqing Yang, Shaohui Ma, Hao Sun, Xiaochao Zhang   +9 more
wiley   +1 more source

A Drosophila model of prion disease and its metabolic changes in the brain

Animal Models and Experimental Medicine, EarlyView.
We developed a Drosophila model for prion disease, and flies were capable of expressing the hamster prion protein (HaPrP) under the control of the GAL4/UAS system. The model exhibited some characteristics of the disease in mammals and displayed alterations in protein, sphingolipid, and carbohydrate metabolism. Preliminary applications have demonstrated
Dongdong Wang, Zhixin Sun, Pei Wen, Mengyang Zhao, Yuheng He, Fengting Gou, Jingjing Wang, Qing Fan, Xueyuan Li, Tianying Ma, Xiaoyu Wang, Wen Li, Sen Chen, Deming Zhao, Lifeng Yang   +14 more
wiley   +1 more source

Advances in Multiple Sclerosis. [PDF]

Biomedicines
Rivera VM.
europepmc   +1 more source

Multiple low dose streptozotocin‐induced diabetes as a model for studying autoimmune diabetes in humans

Animal Models and Experimental Medicine, EarlyView.
Multiple low dose streptozotocin‐induced diabetes is a valuable animal model of diabetes type 1. It should be improved by further research on autoantigens, microbiota and mucosal immune cells from the gut, but also from other organs. Abstract The autoimmune response directed against pancreatic β cells is the most essential pathogenic process in type 1 ...
Ivan Koprivica, Suzana Stanisavljević, Dragica Mićanović, Ivana Stojanović, Đorđe Miljković   +4 more
wiley   +1 more source

Natural killer cells in multiple sclerosis: foe or friends? [PDF]

Front Cell Neurosci
Aghaee F, Abedinpour M, Anvari S, Saberi A, Fallah A, Bakhshi A.   +5 more
europepmc   +1 more source

OPTIC NERVE INVOLVEMENT AND DIPLOPIA AS INITIAL MANIFESTATIONS OF MULTIPLE SCLEROSIS

, 1968
Uri Leibowitz, Milton Alter
openalex   +1 more source

Research advances in dysphagia animal models

Animal Models and Experimental Medicine, EarlyView.
This review systematically summarizes the establishment, evaluation, and detection of dysphagia animal models in stroke, Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS) in three kinds of experimental animals (including rodents, nonhuman primates, and other mammals), providing a basis for the selection of appropriate animal models of ...
Junhui Bai, Keling Cheng, Nannan Zhang, Yunfang Chen, Jun Ni, Zhiyong Wang   +5 more
wiley   +1 more source

Multiomics integration prioritizes potential drug targets for multiple sclerosis. [PDF]

Proc Natl Acad Sci U S A
Jiang Y, Liu Q, Stridh P, Kockum I, Olsson T, Alfredsson L, Diaz-Gallo LM, Jiang X.   +7 more
europepmc   +1 more source