Results 321 to 330 of about 6,495,609 (392)

Smouldering disease in paediatric-onset multiple sclerosis. [PDF]

EBioMedicine
Filippi M, Margoni M, Banwell B, Chitnis T, Dale R, Fadda G, Hacohen Y, Krupp LB, Preziosa P, Yeh EA, Waubant E, Rocca MA.   +11 more
europepmc   +1 more source

Research Progress on Idebenone in Neurodegenerative Diseases

AGING MEDICINE, EarlyView.
The study not only summarizes the biological properties of Idebenone (IDE), including its role in improving mitochondrial function and antioxidative stress, but also explores its clinical research progress in various neurodegenerative diseases, providing a new perspective for the treatment of these disorders.
Yanqing Zhang, Yanhong Ren, Xiaoran Zhu, Tianhao Liu, Rundong Han, Yuqing Fang, Zhangning Zhao, Fei Mao, Yalin Wang, Xian Li, Xiuhua Li   +10 more
wiley   +1 more source

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

Advanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng, Sharon Ai Er Lam, Wei Chun Lim, Hannah Hui Min Toh, Shi Jun Ang   +4 more
wiley   +1 more source

Skin‐Conformal Myography for Real‐Time Hand Tracking Using a Laser‐Induced Graphene Strain Sensor Array

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
A skin‐conformal wearable device based on laser‐induced graphene is developed for continuous strain measurement across the circumference of the forearm for gesture recognition and hand‐tracking applications. Post material optimization, the strain sensor array is integrated with a wearable wireless readout circuit for real‐time control of a robotic arm,
Vinay Kammarchedu, Monther AlSiyabi, Aida Ebrahimi   +2 more
wiley   +1 more source

Multiple sclerosis: Glial cell activation - Biomarker advances and their translational significance. [PDF]

Sci Prog
Zeng W, Wu H, Huang Y.
europepmc   +1 more source

Predictors of risk of secondary progression in multiple sclerosis. [PDF]

Ther Adv Neurol Disord
Laaksonen S, Sucksdorff M, Vuorimaa A, Kuhle J, Nylund M, Rajander J, Wahlroos S, Matilainen M, Saraste M, Airas L.   +9 more
europepmc   +1 more source

Integrating TSPO-PET imaging with metabolomics for enhanced prognostic accuracy in multiple sclerosis

Daniel Radford‐Smith, Abi G. Yates, Tereza Kačerová, Marjo Nylund, Marcus Sucksdorff, Markus Matilainen, Eline Willemse, Johanna Oechtering, Aleksandra Maleska Maceski, David Leppert, Jens Kühle, Fay Probert, Daniel C. Anthony, Laura Airas   +13 more
openalex   +1 more source

Multiple sclerosis: molecular pathogenesis and therapeutic intervention. [PDF]

Signal Transduct Target Ther
Boutitah-Benyaich I, Eixarch H, Villacieros-Álvarez J, Hervera A, Cobo-Calvo Á, Montalban X, Espejo C.   +6 more
europepmc   +1 more source

Examining the Telehealth Readiness Among Individuals With Multiple Sclerosis. [PDF]

J Patient Exp
Zare F, Rahimi R, Zehtab Hashemi H, Faghani L, Ghaedi G, Nabavi SM.   +5 more
europepmc   +1 more source

Phonological networks remain intact in multiple sclerosis. [PDF]

Neuropsychology
Link A, Lebkuecher AL, Cosgrove AL, Castro N, Chiaravalloti ND, Strober LB, Diaz MT.   +6 more
europepmc   +1 more source