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The Effects of Disease-Modifying Therapies on Optic Nerve Degeneration in Multiple Sclerosis. [PDF]
Eur J NeurolZhang X +7 more
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Seminars in Neurology, 2007
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system that commonly leads to inflammatory and atrophic brain pathology, often causing cognitive impairment. MS-associated cognitive impairment was first described over a century ago.
Ralph Benedict1, Julie Bobholz2
semanticscholar +3 more sources
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system that commonly leads to inflammatory and atrophic brain pathology, often causing cognitive impairment. MS-associated cognitive impairment was first described over a century ago.
Ralph Benedict1, Julie Bobholz2
semanticscholar +3 more sources
Science, 2022
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system of unknown etiology. We tested the hypothesis that MS is caused by Epstein-Barr virus (EBV) in a cohort comprising more than 10 million young adults on ...
Kjetil Bjørnevik +10 more
semanticscholar +1 more source
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system of unknown etiology. We tested the hypothesis that MS is caused by Epstein-Barr virus (EBV) in a cohort comprising more than 10 million young adults on ...
Kjetil Bjørnevik +10 more
semanticscholar +1 more source
Diagnosis and Treatment of Multiple Sclerosis: A Review.
Journal of the American Medical Association (JAMA), 2021Importance Multiple sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system characterized by inflammatory demyelination with axonal transection. MS affects an estimated 900 000 people in the US.
Marisa P. McGinley +2 more
semanticscholar +1 more source
Medicine, 2000
Multiple sclerosis is primarily an inflammatory disorder of the brain and spinal cord in which focal lymphocytic infiltration leads to damage of myelin and axons. Initially, inflammation is transient and remyelination occurs but is not durable. Hence, the early course of disease is characterised by episodes of neurological dysfunction that usually ...
Alastair, Compston, Alasdair, Coles
openaire +5 more sources
Multiple sclerosis is primarily an inflammatory disorder of the brain and spinal cord in which focal lymphocytic infiltration leads to damage of myelin and axons. Initially, inflammation is transient and remyelination occurs but is not durable. Hence, the early course of disease is characterised by episodes of neurological dysfunction that usually ...
Alastair, Compston, Alasdair, Coles
openaire +5 more sources
The Immune Response in Multiple Sclerosis.
Annual Review of Pathology, 2021Multiple sclerosis (MS) is a chronic autoimmune, inflammatory, and neurodegenerative disease that affects the central nervous system (CNS). MS is characterized by immune dysregulation, which results in the infiltration of the CNS by immune cells ...
Sofía Rodríguez Murúa +2 more
semanticscholar +1 more source