Results 331 to 340 of about 6,020,192 (375)
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The fatigue severity scale. Application to patients with multiple sclerosis and systemic lupus erythematosus.

Archives of Neurology, 1989
Fatigue is a prominent disabling symptom in a variety of medical and neurologic disorders. To facilitate research in this area, we developed a fatigue severity scale, subjected it to tests of internal consistency and validity, and used it to compare ...
L. Krupp   +3 more
semanticscholar   +1 more source

Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination

Annals of Neurology, 2000
Multiple sclerosis (MS) is a disease with profound heterogeneity in clinical course, neuroradiological appearance of the lesions, involvement of susceptibility gene loci, and response to therapy.
C. Lucchinetti   +5 more
semanticscholar   +1 more source

IMMUNOLOGY OF MULTIPLE SCLEROSIS

Annual Review of Immunology, 2005
▪ Abstract  Multiple sclerosis (MS) develops in young adults with a complex predisposing genetic trait and probably requires an inciting environmental insult such as a viral infection to trigger the disease. The activation of CD4+autoreactive T cells and their differentiation into a Th1 phenotype are a crucial events in the initial steps, and these ...
Sospedra, Mireia, Martin, Roland
openaire   +5 more sources

Epidemiology of multiple sclerosis

Revue Neurologique, 2016
Multiple sclerosis (MS) is the most frequently seen demyelinating disease, with a prevalence that varies considerably, from high levels in North America and Europe (>100/100,000 inhabitants) to low rates in Eastern Asia and sub-Saharan Africa (2/100,000 population).
Leray, Emmanuelle   +3 more
openaire   +4 more sources

Multiple Sclerosis

Nursing Standard, 1990
The Multiple Sclerosis Society of Great Britain and Northern Ireland has an impressive publication programme which includes booklets, sheets, periodicals, and audio and video cassettes. The Society provides general information for adults and children whose lives arc affected directly or indirectly by MS; lecture notes and resource packs for the health ...
Chris Eberhardie, Chris Eberhardie
openaire   +2 more sources

Multiple sclerosis

2016
Due to its sensitivity to the different multiple sclerosis (MS)-related abnormalities, magnetic resonance imaging (MRI) has become an established tool to diagnose MS and to monitor its evolution. MRI has been included in the diagnostic workup of patients with clinically isolated syndromes suggestive of MS, and ad hoc criteria have been proposed and are
FILIPPI , MASSIMO, Preziosa P, Rocca MA
openaire   +4 more sources

Multiple Sclerosis

Annals of Internal Medicine, 1984
The cause of multiple sclerosis is unknown but seems to be multifactorial. Susceptibility or resistance may be genetically determined; something in the environment interacts with the human host at the proper age to cause biochemical and structural lesions in the central nervous system.
G W, Ellison   +3 more
openaire   +2 more sources

Multiple sclerosis

Immunological Reviews, 2005
Summary:  Multiple sclerosis (MS) is a complex genetic disease associated with inflammation in the central nervous system (CNS) white matter and is thought to be mediated by autoimmune processes. Clonal expansion of B cells, their antibody products, and T cells, hallmarks of inflammation in the CNS, are found in MS.
David A, Hafler   +5 more
openaire   +2 more sources

The immunology of multiple sclerosis

Nature reviews. Immunology, 2022
K. Attfield   +4 more
semanticscholar   +1 more source

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