Blood RNA-Seq profiling reveals a set of circular RNAs differentially expressed in frail individuals
Immunity & Ageing, 2023 Background Frailty is an intermediate and reversible geriatric syndrome that often precedes dependence. Therefore, its identification is essential to prevent dependence. Several molecules have been proposed as biomarkers of frailty, but none of them have
Leire Iparraguirre +6 more
doaj +1 more source
The Role of Microorganisms in the Etiopathogenesis of Demyelinating Diseases
Life, 2023 Multiple sclerosis (MS), neuromyelitis optica (NMO) and myelin oligodendrocyte glycoprotein antibody disease (MOGAD) are inflammatory diseases of the central nervous system (CNS) with a multifactorial aetiology.
Jessica Frau +4 more
doaj +1 more source
The clinical- and cost-effectiveness of functional electrical stimulation and ankle-foot orthoses for foot drop in Multiple Sclerosis: a multicentre randomized trial [PDF]
, 2019 Objective: To compare the clinical- and cost-effectiveness of ankle-foot orthoses (AFOs) and functional electrical stimulation (FES) over 12 months in people with Multiple Sclerosis with foot drop.
Bowers, Roy +7 more
core +2 more sources
Objective identification of upper limb tremor in multiple sclerosis using a wrist-worn motion sensor: establishing validity and reliability [PDF]
, 2017 Introduction Over 25% of people with multiple sclerosis experience tremor, which may impact on activities of daily living and quality of life. Yet there is no method to objectively measure tremor and effectiveness of interventions on tremor.
Preston, Jenny +3 more
core +2 more sources
Nature Communications, 2019 Genome-wide association studies (GWAS) have so far uncovered more than 200 loci for multiple sclerosis (MS). Here, the authors integrate data from various sources for a cell type-specific pathway analysis of MS GWAS results that specifically highlights ...
International Multiple Sclerosis Genetics Consortium
doaj +1 more source
Neuroprotection in a Novel Mouse Model of Multiple Sclerosis [PDF]
, 2013 The authors acknowledge the support of the Barts and the London Charity, the Multiple Sclerosis Society of Great Britain and Northern Ireland, the National Multiple Sclerosis Society, USA, notably the National Centre for the Replacement, Refinement ...
A Compston +49 more
core +4 more sources
Anger, Quality of Life and Mood in Multiple Sclerosis [PDF]
, 2015 This research was funded by The Multiple Sclerosis Society (UK).Peer reviewedPublisher ...
Cooper, Clare L +4 more
core +1 more source
Global, regional, and national burden of multiple sclerosis 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. [PDF]
, 2018 BACKGROUND: Multiple sclerosis is the most common inflammatory neurological disease in young adults. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic method of quantifying various effects of a given condition by
GBD 2016 Multiple Sclerosis Collaborators
core +1 more source
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source