Results 41 to 50 of about 6,020,093 (278)

Reduction in circulating vitamin D binding protein in patients with multiple sclerosis

open access: yesBMC Neurology, 2021
Background In this study, we aimed to determine the risk association between vitamin D binding protein (VDBP) polymorphism in patients with multiple sclerosis (MS) in a MS biobank and the difference in VDBP serum levels in MS patients who were recently ...
Zhila Maghbooli   +4 more
doaj   +1 more source

Benchmarking Continuous Time Models for Predicting Multiple Sclerosis Progression [PDF]

open access: yesarXiv, 2023
Multiple sclerosis is a disease that affects the brain and spinal cord, it can lead to severe disability and has no known cure. The majority of prior work in machine learning for multiple sclerosis has been centered around using Magnetic Resonance Imaging scans or laboratory tests; these modalities are both expensive to acquire and can be unreliable ...
arxiv  

Interleukin-33 plasma levels in patients with relapsing-remitting multiple sclerosis

open access: yesBiomolecular Concepts, 2017
Cytokines are implicated in the immunopathogenesis of multiple sclerosis (MS). Interleukin (IL)-33, one of the recently discovered members of the IL-1 superfamily, is a dual functional cytokine involved in various autoimmune disorders.
Alsahebfosoul Fereshteh   +6 more
doaj   +1 more source

Handling changes in MRI acquisition parameters in modeling whole brain lesion volume and atrophy data in multiple sclerosis subjects: Comparison of linear mixed-effect models

open access: yesNeuroImage: Clinical, 2015
Magnetic resonance imaging (MRI) of the brain provides important outcome measures in the longitudinal evaluation of disease activity and progression in MS subjects. Two common measures derived from brain MRI scans are the brain parenchymal fraction (BPF)
Alicia S. Chua, MS   +8 more
doaj   +1 more source

Multiple sclerosis.

open access: yesClinical evidence, 2002
▪ Abstract  Multiple sclerosis (MS) is a common inflammatory disease of the central nervous system (CNS). Diagnosis rests upon identifying typical clinical symptoms and interpreting supportive laboratory and radiological investigations. The etiology is unknown; however, strong evidence suggests that MS is an autoimmune disease directed against CNS ...
Mike, Boggild, Helen, Ford
  +9 more sources

Pregnancy-Induced Changes in microRNA Expression in Multiple Sclerosis

open access: yesFrontiers in Immunology, 2021
Pregnancy affects the disease course in multiple sclerosis (MS), particularly in the third trimester, where the relapse rate is reduced by as much as two thirds.
Helle Bach Søndergaard   +6 more
doaj   +1 more source

Effectiveness of regional diffusion MRI measures in distinguishing multiple sclerosis abnormalities within the cervical spinal cord [PDF]

open access: yes, 2021
Multiple sclerosis is an inflammatory disorder of the central nervous system. Quantitative MRI has huge potential to provide intrinsic and normative values of tissue properties useful for diagnosis, prognosis and ultimately clinical follow-up of this disease.
arxiv   +1 more source

A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis

open access: yesNature Communications, 2019
Genome-wide association studies (GWAS) have so far uncovered more than 200 loci for multiple sclerosis (MS). Here, the authors integrate data from various sources for a cell type-specific pathway analysis of MS GWAS results that specifically highlights ...
International Multiple Sclerosis Genetics Consortium
doaj   +1 more source

The Role of Microorganisms in the Etiopathogenesis of Demyelinating Diseases

open access: yesLife, 2023
Multiple sclerosis (MS), neuromyelitis optica (NMO) and myelin oligodendrocyte glycoprotein antibody disease (MOGAD) are inflammatory diseases of the central nervous system (CNS) with a multifactorial aetiology.
Jessica Frau   +4 more
doaj   +1 more source

Blood RNA-Seq profiling reveals a set of circular RNAs differentially expressed in frail individuals

open access: yesImmunity & Ageing, 2023
Background Frailty is an intermediate and reversible geriatric syndrome that often precedes dependence. Therefore, its identification is essential to prevent dependence. Several molecules have been proposed as biomarkers of frailty, but none of them have
Leire Iparraguirre   +6 more
doaj   +1 more source

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