Results 91 to 100 of about 466,412 (376)

Blood exosome connexins and small RNAs related to demyelinating disease activity

Annals of Clinical and Translational Neurology, Volume 12, Issue 3, Page 538-555, March 2025.
Abstract Objectives To assess blood exosome (Ex)‐connexin (Cx)43 (encoded by GJA1) and its truncated isoforms in multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD), which show distinct alterations in astroglial Cx43. Methods Serum Exs from 48 patients with MS (34 relapsing–remitting, 14 secondary‐progressive), 35 with NMOSD, 20 ...
Guzailiayi Maimaitijiang, Jun‐ichi Kira, Yuri Nakamura, Mitsuru Watanabe, Ezgi Ozdemir Takase, Satoshi Nagata, Ayako Sakoda, Xu Zhang, Katsuhisa Masaki, Ryo Yamasaki, Noriko Isobe, Hiroo Yamaguchi, Tomohiro Imamura   +12 more
wiley   +1 more source

Translation and validation of the Persian version of Godin Leisure-Time Exercise Questionnaire in patients with multiple sclerosis

BMC Neurology, 2021
Study Design Psychometric study. Objective The purpose of this study is to translate, culturally adapt and evaluate the validity and reliability of the Persian (Farsi) version of GLTEQ in patients with multiple sclerosis.
Mohammad-Reza Fattahi, Pardis Noormohammadpour, Meysam Ramezani, Mohammad Ali Sahraian, Mohammad Ali Mansournia, Mastaneh Rajabian Tabesh, Mohamed Ali Mesgarof, Maryam Abolhasani   +7 more
doaj   +1 more source

Correlation of multiple sclerosis (MS) incidence trends with solar and geomagnetic indices: time to revise the method of reporting MS epidemiological data [PDF]

Iranian Journal of Neurology 2014; 13(2):64-69, 2014
Background: Recently, we introduced solar related geomagnetic disturbances (GMD) as a potential environmental risk factor for multiple sclerosis (MS). The aim of this study was to test probable correlation between solar activities and GMD with long-term variations of MS incidence.
arxiv  

A Bibliography of Multiple Sclerosis Lesions Detection Methods using Brain MRIs [PDF]

arXiv, 2023
Introduction: Multiple Sclerosis (MS) is a chronic disease that affects millions of people across the globe. MS can critically affect different organs of the central nervous system such as the eyes, the spinal cord, and the brain. Background: To help physicians in diagnosing MS lesions, computer-aided methods are widely used.
arxiv  

An MRI assessment of mechanisms underlying lesion growth and shrinkage in multiple sclerosis

Annals of Clinical and Translational Neurology, Volume 12, Issue 4, Page 686-700, April 2025.
By applying the tensor model, we analysed lesion orientation and the directionality of lesion expansion/contraction in multiple sclerosis. Each lesion is summarized as an ellipsoid, and the tensor model is applied to calculate lesion anisotropy. From the top to the bottom white matter atlas, surface‐in gradient segmentation and venous atlas used in the
Ermelinda De Meo, Ferran Prados Carrasco, J. William L. Brown, Alasdair J. Coles, Nick G. Cunniffe, Amy E. Jolly, Baris Kanber, Rebecca Samson, Frederik Barkhof, Declan Chard   +9 more
wiley   +1 more source

Knowledge Is Power, but Is Ignorance Bliss? Optimising Conversations About Disease Progression in Multiple Sclerosis

Neurology and Therapy, 2019
Communication about multiple sclerosis (MS) disease progression between healthcare professionals (HCPs) and people with MS (PwMS) has historically been considered difficult, and attention to improving it has been neglected.
Patrick Vermersch, Jane Shanahan, Dawn Langdon, David Yeandle, Nektaria Alexandri, Sven Schippling   +5 more
doaj   +1 more source

Gait Assessment for Multiple Sclerosis Patients Using Microsoft Kinect [PDF]

arXiv, 2015
Gait analysis of patients with neurological disorders, including multiple sclerosis (MS), is important for rehabilitation and treatment. The Mircrosoft Kinect sensor, which was developed for motion recognition in gaming applications, is an ideal candidate for an inexpensive system providing the capability for human gait analysis.
arxiv  

Multiple Sclerosis disease: a computational approach for investigating its drug interactions [PDF]

arXiv, 2020
Multiple Sclerosis (MS) is a chronic and potentially highly disabling disease that can cause permanent damage and deterioration of the central nervous system. In Europe it is the leading cause of non-traumatic disabilities in young adults, since more than 700,000 EU people suffer from MS. Although recent studies on MS pathophysiology have been provided,
arxiv  

Latent Space Analysis of VAE and Intro-VAE applied to 3-dimensional MR Brain Volumes of Multiple Sclerosis, Leukoencephalopathy, and Healthy Patients [PDF]

arXiv, 2021
Multiple Sclerosis (MS) and microvascular leukoencephalopathy are two distinct neurological conditions, the first caused by focal autoimmune inflammation in the central nervous system, the second caused by chronic white matter damage from atherosclerotic microvascular disease.
arxiv  

Participant recruitment into a randomised controlled trial of exercise therapy for people with multiple sclerosis [PDF]

, 2015
The success of a clinical trial is often dependant on whether recruitment targets can be met in the required time frame. Despite an increase in research into the benefits of exercise in people with multiple sclerosis (PwMS), no trial has reported ...
A Carter, A Carter, A Daley, AE Latimer-Cheung, AM McDonald, AM McDonald, Amanda Daley, Anouska Carter, AS Lindblad, Basil Sharrack, C Cooper, C Ott, CH Polman, D Moher, D Nary, G Godin, J Tosh, Jane Petty, JF Kurtzke, JL Probstfield, JM Saxton, John Saxton, Liam Humphreys, M Asano, MJ Sá, Nicky Snowdon, Nicola Woodroofe, RE Rdesinski, RE Taylor-Piliae, RW Motl, S Thomas, S Treweek, X Montalban   +32 more
core   +2 more sources