Results 161 to 170 of about 421,641 (311)

AXL Promotes Ischemic Myelin Repair Through Alleviating Myelin Debris Deposition and Lipid Droplets Accumulation

Advanced Science, EarlyView.
Microglial AXL drives white matter repair after stroke by orchestrating the cleanup of myelin debris. Mechanistically, AXL signals through EGR1 to boost Smpd1 transcription, regulating sphingolipid metabolism and preventing lipid droplet toxicity. Restoring the pathway with ASM therapy mitigates damage, positioning AXL as a key node for therapeutic ...
Junqiu Jia, Yonghui Gan, Jia Li, Lilin Li, Hailan Meng, Min Sun, Lei Ye, Rui Mao, Xiang Cao, Shengnan Xia, Xinyu Bao, Renyuan Liu, Meijuan Zhang, Yun Xu   +13 more
wiley   +1 more source

Proposing Strategies to Increase Pregnancy-Related Awareness Among Multiple Sclerosis Patients in Iran [PDF]

Neurology Letters
Elnaz Asadollahzadeh, Sam Daneshvar
doaj   +1 more source

The Expanding Clinical Spectrum of Myelin Oligodendrocyte Glycoprotein (MOG) Antibody Associated Disease in Children and Adults

Frontiers in Neurology, 2020
Erica Parrotta, Ilya Kister
doaj   +1 more source

Can Augmented Reality Head-Mounted Display Exergames Support the Management of Multiple Sclerosis at Home? Workshop Discussions with Researchers and Experts with Lived Experience of MS [PDF]

Michelle Adiwangsa, Hanna Suominen, Penny Sweetser   +2 more
openalex   +1 more source

Reprogramming M2b Macrophages via GPX1 Activation by Selenium Nanoparticles Attenuates Lupus Nephritis

Advanced Science, EarlyView.
SeZM NPs selectively target M2b macrophages through mannose–MRC1 (CD206) recognition, enhance GPX1 biosynthesis, and suppress mitochondrial ROS generation, oxidative stress, and JAK–STAT signaling. This dual regulation reduces pro‐inflammatory cytokine release, limits immune cell infiltration and fibrosis, and preserves renal function, providing a ...
Haoran Lv, Guanning Huang, Hongyu Li, Hanzhi Liang, Huajing Peng, Kefei Wu, Wenfang Chen, Dandan Zhang, Kexin Ma, Yufei Du, Siweier Luo, Yi Zhou, Haiping Mao, Wei Chen, Tianfeng Chen, Yiming Zhou, Qinghua Liu   +16 more
wiley   +1 more source

Onabotulinumtoxin intra-detrusor injection for lower urinary tract symptoms (LUTS) in patients with multiple sclerosis (MS): A systematic review and meta-analysis. [PDF]

Caspian J Intern Med
Soltanzadi A, Mirmosayyeb O, Momeni Moghaddam A, Vaheb S, Ghajarzadeh M.   +4 more
europepmc   +1 more source

Antibody‐Empowered Nanomedicine for Precise Biomedical Applications

Advanced Science, EarlyView.
This review explores strategies for functionalizing nanoparticles with antibodies to construct antibody‐empowered nanomedicine. It discusses the classification of these nanomedicines based on antibody structure, with a specific focus on their biomedical applications in diagnostics, bioimaging, and therapeutics for various diseases.
Chen Chen, Xinglin Chen, Zhenhao Gao, Meng Sun, Yaozong Yu, Fang Lv, Qiujun Wang, Jinfeng Zhang   +7 more
wiley   +1 more source

Epstein-Barr virus infection and vitamin D deficiency are both "causal" for multiple sclerosis (MS) - could the common denominator be their effects on hepcidin levels? [PDF]

Metab Brain Dis
van Rensburg SJ, van Toorn R, Jaftha M, Kemp MC, Engel-Hills P, Kotze MJ.   +5 more
europepmc   +1 more source

Good multiple sclerosis (MS) care and how to get there in Canada: Perspectives of Canadian healthcare providers working with persons with MS. [PDF]

Front Neurol, 2023
Petrin J, Marrie RA, Devonshire V, Jichici D, Hrebicek O, Metz LM, Morrow SA, Oh J, Smyth P, Donkers SJ.   +9 more
europepmc   +1 more source

Individualised behaviour change strategies for physical activity in multiple sclerosis (IPAC-MS): protocol for a randomised controlled trial [PDF]

, 2019
Farren L. Goulding, Charity Evans, Katherine Knox, Hyun J. Lim, Michael C. Levin, Sarah J. Donkers   +5 more
openalex   +1 more source