Background Multiple sclerosis (MS) is a leading cause of neurological disability among young and middle-aged adults worldwide, and disability is measured using a variety of approaches, including patient reported outcome measures (PROMs) such as the ...
Robert Motl+11 more
doaj +1 more source
Feasibility of a co-designed online nutrition education program for people with multiple sclerosis [PDF]
Objective: Diet quality is important for people with multiple sclerosis (MS), but conflicting online information causes them confusion. People with MS want evidence-based MS-specific information to help them make healthy dietary changes, and we co-designed an asynchronous, online nutrition education program (Eating Well with MS) with the MS community ...
arxiv
ATTENUATED HR AND BLOOD PRESSURE RESPONSE TO ISOMETRIC EXERCISE IN MULTIPLE SCLEROSIS (MS) 472
E. B. Pepin, Jennifer A. Taylor
openalex +1 more source
IL-10–expressing adult neural stem cells for treatment of autoimmune encephalitis and multiple sclerosis (MS) [PDF]
openalex +1 more source
This study uncovers that stress granules (SGs) are involved in the pathogenesis of Parkinson's disease (PD). Perillaldehyde (PAE) can improve Parkinson‐like deficits in preclinical models by directly binding to G3BP and instigating liquid–liquid phase separation (LLPS) of G3BP.
Minglv Fang+12 more
wiley +1 more source
Development of a patient reported outcome scale for fatigue in multiple sclerosis: The Neurological Fatigue Index (NFI-MS) [PDF]
Roger Mills+3 more
openalex +1 more source
High Fat Low Carbohydrate Diet Is Linked to CNS Autoimmunity Protection
Mapping global epidemiological data to macronutrient supply reveals high carbohydrate, in contrast to high fat supply, associates with increased multiple sclerosis (MS) prevalence and incidence. This is confirmed in a mouse MS model, experimental autoimmune encephalomyelitis (EAE), using isocaloric diets: a high carbohydrate diet aggravates, a high ...
Duan Ni+15 more
wiley +1 more source
Retracted: Retinal OCT Texture Analysis for Differentiating Healthy Controls from Multiple Sclerosis (MS) with/without Optic Neuritis. [PDF]
International BR.
europepmc +1 more source
Mutations in hnRNP A1 drive neurodegeneration and alternative RNA splicing of neuronal gene targets
RNA binding protein dysfunction is a pathogenic feature of multiple neurological diseases, including multiple sclerosis (MS). Neurodegeneration (the loss of, or damage to neurons and axons) is the primary driver of disease progression in MS.
Ansalna Ansari+4 more
doaj
Using integrative multi‐omics analyses, this study maps FIIN‐2's targets and signaling networks in liver cancer cells, and identifies covalent AMPKα1 binding as a novel autophagy‐activating mechanism. The findings resolve both on‐target FGFR inhibition and off‐target protein engagement, providing a molecular roadmap to refine covalent kinase inhibitors
Ying Fu+9 more
wiley +1 more source