Results 291 to 300 of about 466,412 (376)

Autologous Nonmyeloablative Hematopoietic Stem Cell Transplantation for Diffuse Cutaneous Systemic Sclerosis: Identifying Disease Risk Factors for Toxicity and Long‐Term Outcomes in a Prospective, Single‐Arm Trial

open access: yesArthritis &Rheumatology, Volume 77, Issue 5, Page 571-581, May 2025.
Objective Two randomized trials for patients with diffuse systemic sclerosis (SSc) demonstrated an overall survival (OS) and event‐free survival (EFS) advantage of autologous hematopoietic stem cell transplantation (AHSCT) using CD34+ selected peripheral blood stem cells (PBSCs) compared with monthly cyclophosphamide (CY).
George E. Georges   +16 more
wiley   +1 more source

Current use of fluid biomarkers as outcome measures in Multiple Sclerosis (MS): a review of ongoing pharmacological clinical trials. [PDF]

open access: yesNeurol Sci
Schilke ED   +8 more
europepmc   +1 more source

Metabolic Stress Expands Polyfunctional, Proinflammatory Th17 Cells in Patients With Psoriatic Arthritis for Whom There is Interleukin‐23–Independent Interleukin‐17 Production

open access: yesArthritis &Rheumatology, EarlyView.
Objective Genetic associations and blockade of the interleukin (IL)‐23/IL‐17 axis with monoclonal antibodies support a role for this pathway in patients with psoriatic arthritis (PsA). This study examines the requirement of IL‐23 for IL‐17 production and the role of the metabolic microenvironment in the expansion of Th17‐derived cells in patients with ...
Carmel B. Stober   +4 more
wiley   +1 more source

RSEA: A Web Server for Pathway Enrichment Analysis of Metabolic Reaction Sets

open access: yesBiotechnology and Bioengineering, EarlyView.
Reaction Set Enrichment Analysis (RSEA), a web server tool designed for metabolic pathway enrichment analysis of reaction sets derived from genome‐scale metabolic models was introduced. RSEA converts given reaction lists into standardized identifiers and statistically evaluates their enrichment across metabolic pathways.
Merve Yarıcı   +4 more
wiley   +1 more source

Neural electrodes for brain‐computer interface system: From rigid to soft

open access: yesBMEMat, EarlyView.
Here, we review the development trends of neural electrodes in BCI. This paper highlights the critical role of electrodes in BCI systems, analyzes the limitations of rigid electrodes, and introduces various flexible electrodes. Furthermore, we discuss application scenarios and prospects of BCI electrode technology, aiming to provide valuable references
Dan Yang   +7 more
wiley   +1 more source

Morphology of the sternoclavicular joint and its microanatomical changes in response to osteoarthritic degeneration

open access: yesClinical Anatomy, EarlyView.
Abstract Although the sternoclavicular joint shares structural similarities with the knee and hip joints as a diarthrodial joint, its biomechanics differ significantly due to its non‐weight‐bearing nature. Nevertheless, it is subject to considerable loading, leading to increased susceptibility to osteoarthritis, a prevalent condition characterized by ...
Sophie Mok   +4 more
wiley   +1 more source

Cuproplasia and cuproptosis, two sides of the coin

open access: yesCancer Communications, Volume 45, Issue 5, Page 505-524, May 2025.
Abstract Copper is an essential micronutrient in the human body, mainly acting as a crucial cofactor required for a wide range of physiological processes across nearly all cell types. Recent advances revealed that tumor cells seize copper to fulfill their rapid proliferation, metastasis, immune evasion, and so on by reprogramming the copper regulatory ...
Kaizhong Lu   +4 more
wiley   +1 more source

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