Prediction of First and Recurrent Falls in Parkinson's Disease
Objective To develop and externally validate prediction models for next‐year falls in Parkinson's disease (PD), and to evaluate the incremental value of imaging and fluid biomarkers. Methods We developed models in Parkinson's Progression Markers Initiative (PPMI) to predict next‐year falls with external validation in University of Pennsylvania (UPenn ...
Joaquin A. Vizcarra +13 more
wiley +1 more source
Sex work or male-with-male sexual activity and the risks of HIV and hepatitis C acquisition among people who inject drugs: a global systematic review and meta-analysis. [PDF]
Dawe J +44 more
europepmc +1 more source
Abstract Factors varying along elevational gradients impose strong aerodynamic and physiological constraints on powered flight, yet the internal microanatomical variation associated with elevational context in animals under such conditions remains poorly understood.
Juan Camilo Ríos‐Orjuela +5 more
wiley +1 more source
Partnering With Lived Experience Experts to Co-Design and Co-Facilitate Trauma-Informed Practice Training for Health Professionals: Evaluation Findings. [PDF]
Ciftci S +7 more
europepmc +1 more source
Exceptional preservation informs the paleobiology of tapinocephalid dinocephalians
Abstract The tapinocephalid dinocephalian Moschops is one of the most iconic taxa of the middle Permian, yet its paleobiology remains one of the least well‐known. Here, we address some aspects of paleoneurology and paleobiology of Moschops using CT scanning of four well preserved skulls from the upper Abrahamskraal Formation of South Africa. Two of the
Julien Benoit +6 more
wiley +1 more source
Impact of violence on HIV outcomes among female sex workers: A global systematic review and meta-analysis. [PDF]
Dawe J +12 more
europepmc +1 more source
Objective CD4 T cells specific for citrullinated (cit) peptides are key players in rheumatoid arthritis (RA) immunopathogenesis. Characterizing these cells and identifying features of healthy and RA‐associated autoreactivity will provide valuable insight into disease mechanisms and form the basis of immune state biomarkers to facilitate the next ...
James A. Stanway +13 more
wiley +1 more source
Linking maternal childhood maltreatment to health-related and psychosocial risk factors during pregnancy: intergenerational implications for early child development. [PDF]
Reyentanz E +4 more
europepmc +1 more source
Objective DISSOLVE I and II examined the efficacy and safety of nanoencapsulated sirolimus (NAS) plus pegadricase (NASP) in patients with uncontrolled gout (UG). Methods In these double‐blind, placebo‐controlled Phase 3 trials of NASP, patients were randomized 1:1:1 to infusions of high‐dose (HD) or low‐dose (LD) NAS plus pegadricase (HD NASP, LD NASP,
Herbert S. B. Baraf +15 more
wiley +1 more source
Dynamic shift in the dominant transmission route of clade Ib monkeypox virus across networks with sexual and nonsexual contacts. [PDF]
Miura F +7 more
europepmc +1 more source

