Results 91 to 100 of about 5,909,141 (271)

Associations between lifetime pregnancy and sexual risk behaviors among 15-24-year-old adolescent girls and young women in South Africa: Secondary analyses of the 2016 Demographic Health Survey.

PLOS Global Public Health
Adolescent girls and young women (AGYW) in South Africa are highly vulnerable to HIV and poor sexual and reproductive health (SRH) outcomes. Interventions must respond to the unique needs of different AGYW groups, such as AGYW who have ever been pregnant.
Ololade Julius Baruwa
doaj   +1 more source

Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution

Advanced Science, EarlyView.
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley   +1 more source

Oral and anal sex practices among high school youth in Addis Ababa, Ethiopia

BMC Public Health, 2012
Background Understanding the full range of sexual behaviors of young people is crucial in developing appropriate interventions to prevent and control sexually transmitted infections including HIV.
Cherie Amsale, Berhane Yemane
doaj   +1 more source

Sexual behaviour patterns in South Africa and their association with the spread of HIV: insights from a mathematical model [PDF]

This paper aims to quantify the effects of different types of sexual risk behaviour on the spread of HIV in South Africa. A mathematical model is developed to simulate changes in numbers of sexual partners, changes in marital status, changes in ...
Leigh Johnson, Thomas Rehle, Debbie Bradshaw, Victoria Pillay-Van Wyk, Rob Dorrington   +4 more
core  

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

Advanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang, Ziyao Wang, Dongyue Zuo, Zhaowen Su, Bowen Song, Jiamin Gao, Yizhou Zhang, Ruiting Zhao, Linjie Sun, Mengdi Li, Yirui Fan, Dandan Geng, Lei Wang   +12 more
wiley   +1 more source

Multiple concurrent partnerships and sexual dissatisfaction - an exploratory study among black women in South Africa. [PDF]

, 2011
This research report focuses on the linkages between multiple concurrent partnerships and sexual dissatisfaction in a sample of black women. Multiple Concurrent Partnerships has been identified as a key driver of HIV/AIDS in Southern Africa and it has ...
Rassool, Rayana
core  

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source

Weighted prevalence and 95% confidence intervals of self-reported HIV high-risk behaviour, condomless casual partnerships, transactional partnerships, condomless last sex and both multiple sexual partnership and condomless last sex by sex across 14 PHIA surveys.

Weighted prevalence and 95% confidence intervals of self-reported HIV high-risk behaviour, condomless casual partnerships, transactional partnerships, condomless last sex and both multiple sexual partnership and condomless last sex by sex across 14 PHIA ...
Katrina Sleeman (780057), Negussie Taffa (18309449), Rose Nyirenda (5537069), Christina Mwangi (14797286), Hermann Brou (82547), Kondwani Nkanaunena (775132), Appolonia Aoko (694817), Anita Beukes (14797283), Stephane Bodika (16447121), Judith D. Shang (18309422), Choice Ginindza (11785772), Alexandre K. Ekra (18309425), Ray W. Shiraishi (9234298), Peter A. Minchella (3779905), Shirley Lecher (14797265), George S. Mgomella (17002074), Mtemwa K. Nyangulu (18309443), Fred M. Asiimwe (18309440), Celestine Nyagatare (18309458), Man E. Charurat (9344613), Werner M. Maokola (11127761), Yimam G. Misganie (18309431), Mohamed F. Jalloh (9253638), Andrew C. Voetsch (9167418), Ibrahim Dalhatu (3340230), Sileshi Lulseged Desta (18309434), Rose Wafula (18309437), Jennifer A. Nel (18309464), Eboi Ehui (10021571), Anne-Cecile Z. Bissek (18309419), Sindisiwe S. Dlamini (18309428), Clement B. Ndongmo (9167415), Kyle Milligan (15572329), Lucy Okell (224005), Hetal K. Patel (10692384), Collins Kamanzi (18309455), Gallican N. Rwibasira (11567195), Elisabeth Mungai (18309470), Frehywot Eshetu (11262483), Matthias Alagi (11457261), Melodie A. Nasr (18309467), Harriet Nuwagaba-Biribonwoha (164669), Andrew A. Abutu (18309452), Helen Chun (3125136), Johannes O. Klemens (18309446), Gambo Aliyu (411491), Olanrewaju Edun (18309416), Wilford L. Kirungi (18309461), Emilio Dirlikov (4117021), Gloria Gonese (10221070), Jeffrey W. Imai-Eaton (16942964), Sasi Jonnalagadda (12119133), Thomas N. O. Achia (7194763)   +52 more
core   +1 more source

OTUD6A‐Mediated Deubiquitination of PRDX1 Protects Against Oral Ulcer by Restoring Mitochondrial Function

Advanced Science, EarlyView.
In human oral keratinocytes, OTUD6A promoted cell migration by deubiquitinating and stabilizing PRDX1. Conversely, OTUD6A deficiency reduced PRDX1 stability, triggering mitochondrial dysfunction and aggravating OU progression. ABSTRACT Oral ulcers (OU), as the most highly prevalent and recurrent oral mucosal lesion, have an unclear pathogenesis that ...
Xiaoyu Sun, Ruiwei Jia, Xingbei Pan, Rui Huang, Jiahong Chen, Ziyi Yao, Lei Yin, Jun Ma, Hongjieliang Wang, Xinyu Huang, Yilin Ma, Yifan Ping, Yuanyuan Chen, Huining Wang, Shengbin Huang, Guang Liang   +15 more
wiley   +1 more source

Dynamics of multiple sexual signals in relation to climatic conditions [PDF]

, 2007
Question: Can trait-specific phenotypic plasticity in response to annual environmental variation lead to changes in the strength of sexual selection through the relative expression of sexual ornaments at the population level?
Rosivall, Bal\ue1zs, Hegyi, Gergely, Török, János, Szöllösi, Eszter, Rosivall, Balázs, T\uf6r\uf6k, J\ue1nos, Garamszegi, L\ue1szl\uf3, Garamszegi, László Zsolt, Hargitai, Rita   +8 more
core   +1 more source