A fully synthetic four‐component vaccine has been developed combining Tn antigen, vizantin (Mincle agonist), rhamnose (antibody recruitment), and mannose (CD206 targeting). By synergistically activating Mincle, FcγR, and CD206 pathways, it elicits strong IgG switching and cytotoxic T‐cells, significantly inhibiting tumors in mice.
Wenbo Ming +9 more
wiley +1 more source
MSRRT-DETR: A high-precision apple detection method with strong cross-domain generalization capability in complex orchard scenes. [PDF]
Zhang X +9 more
europepmc +1 more source
Employing a digital single‐molecule activity tracker (dSMAT), this research demonstrates that high‐photon‐flux irradiation drives progressive oxidative scarring in polymerases. Unlike simple thermal denaturation, real‐time kinetic tracking dynamically visualizes enzymes degrading into multiple impaired subpopulations.
Anran Zheng +11 more
wiley +1 more source
Enhancing physical, technical, tactical, and cognitive performance in female youth football players using eye-tracking and neurofeedback training: an exploratory study. [PDF]
Carvalho SA +5 more
europepmc +1 more source
Task‐adaptive programmable optics enables label‐free virtual staining through optical‐attention‐guided acquisition and reconstruction. By optimizing wavelength, illumination angle, exposure time, and imaging depth, the framework learns task‐relevant optical measurements, generating clinically interpretable virtual stains with improved fidelity, non ...
Tianyue He +13 more
wiley +1 more source
Empowering knowledge dissemination: a 5A model for health professionals in IVF health communication through short videos. [PDF]
Dan J, Li S, He L.
europepmc +1 more source
Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS) in Glioblastoma
ABSTRACT Glioblastoma (GBM) remains one of the most challenging brain malignancies due to the restrictive nature of the blood–brain barrier (BBB), which severely limits effective drug and gene delivery. To overcome this, we introduce Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS), a modular platform that enables safe ...
Gulsah Erel‐Akbaba +25 more
wiley +1 more source
The Effects of Mental Fatigue on Psychophysiological Responses, Mood States, and Archery Shooting Performance Under a Simulated Archery Competition: A Randomized Cross-Over Study. [PDF]
Soylu S, Arslan E, Kilit B, Soylu Y.
europepmc +1 more source
An STI‐guided metagenomic association framework links soybean salt‐tolerance phenotypes with rhizosphere microbiome composition and network organization in natural saline soils. The approach identifies candidate beneficial taxa, including Thalassospira xiamenensis, and provides an efficient strategy for mining stress‐protective microbes from native ...
Yu Luo +3 more
wiley +1 more source
Behavioural and electroencephalographic assessment of captive-bolt stunning in kangaroo pouch young. [PDF]
Sharp TM, McLeod SR, Gibson TJ.
europepmc +1 more source

