Deep Learning Prediction of O‐Glycopeptide Tandem Mass Spectra Enhances O‐Glycoproteomics
DeepGPO integrates Transformer and graph neural networks with tailored training strategies, including data augmentation, loss re‐weighting, and pre‐training, to achieve high‐quality O‐glycopeptide MS/MS spectra prediction. The predicted MS/MS spectra are used to localize O‐glycosylation sites from HCD MS/MS data, enhancing O‐glycoproteomics analysis ...
Yu Zong, Yuxin Wang, Liang Qiao
wiley +1 more source
Physical Health Challenges, Healthcare Needs, and Barriers to Care among Firearm Injury Survivors: A Mixed Methods Analysis. [PDF]
Semenza DC +5 more
europepmc +1 more source
Plant‐based nanomaterials derived from alfalfa serve as dual‐function catalysts, coupling photodegradation and phytoremediation to degrade polyethylene under UV‐A light and in soil. The nanomaterials work synergistically with alfalfa and soil microbes, achieving efficient plastic breakdown without trophic transfer.
Haoran Liu +4 more
wiley +1 more source
Examining disparities in harmful reporting on community firearm violence in Philadelphia television news reports. [PDF]
Beard JH +9 more
europepmc +1 more source
Highly overlapping fluorescent signals become distinguishable in photon‐limited living organisms via advanced imaging with intelligent reconstruction. The resulting in vivo hyperspectral imaging capability reveals nanoplastic uptake and circulation in live zebrafish, providing a new approach for studying complex biological and environmental processes ...
Renjian Li +11 more
wiley +1 more source
Effects of Cerebellar tACS With Gamma Band on Basketball Shooting Skills: A Single-Blind, Randomized Controlled Trial in College Students With Basketball Experience. [PDF]
Miyaguchi S +4 more
europepmc +1 more source
CLRe: A Synergistic Dual‐Engine Framework for One‐Step Retrosynthesis Prediction
CLRe uses a contrastive difficulty score to order pretrained seq2seq fine‐tuning for retrosynthesis. Reaction embeddings define the ranking score, and a cumulative easy‐to‐hard schedule expands from the easiest subset to the full training set while earlier examples remain active.
Tianhao Su +5 more
wiley +1 more source
A Diagnostic Algorithm for Reconstructing the Direction of Gunshots Using OsiriX and Maya in Living Patients: A Forensic Radiology Approach. [PDF]
Malta G +8 more
europepmc +1 more source
AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li +8 more
wiley +1 more source
The keys to success: personality traits and mental strategies are associated with success indicators in special forces selection. [PDF]
da Silva D +4 more
europepmc +1 more source

