Results 241 to 250 of about 244,730 (294)

A Score-Fusion Method Based on the Sine Cosine Algorithm for Enhanced Multimodal Biometric Authentication. [PDF]

Sensors (Basel)
Hamouda E, Alaerjan AS, Mostafa AM, Tarek M.   +3 more
europepmc   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Diel study reveals increased nighttime bacterial activity and its connection to organic compounds in the ocean. [PDF]

Commun Biol
Liu S, Longnecker K, Vergin K, Bolaños LM, Giovannoni S, Opalk K, Halewood E, Kido Soule MC, Swarr GJ, Parsons R, Maas AE, Gossner H, Blanco-Bercial L, Wittmers F, Worden AZ, Kujawinski EB, Curry R, Johnson R, Carlson CA.   +18 more
europepmc   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Case Report: novel GUCA1B and ABHD12 mutations in retinitis pigmentosa sine pigmento: expanding the genotypic spectrum through multimodal phenotyping. [PDF]

Front Med (Lausanne)
Wu Y, Wang H, Zhang J, Wang X, Wu X, Mao C, Sun Y, Zhou W.   +7 more
europepmc   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Single-phase full-bridge inverter control based on discrete adaptive sliding mode algorithm with error compensation. [PDF]

PLoS One
Zhang Y, Tang Z, Xu F, Zhou K, Yang K.
europepmc   +1 more source

Temporal interference stimulation of peripheral nerves induces functionally diverse limb movements revealed by automated pose estimation and unsupervised behavioral analysis. [PDF]

J Neuroeng Rehabil
Olorocisimo JP, Nag S, Zhang H, Yang S, Prytula M, Liu S, Kanchwala M, Sun Y, Zariffa J, Genov R.   +9 more
europepmc   +1 more source

Design and Experimental Validation of a Round Inductosyn-Based Angular Measurement System. [PDF]

Micromachines (Basel)
Wang J, Wang J, Chen J, Zhong C, Shao Y.
europepmc   +1 more source

Improved WOA-DBSCAN Online Clustering Algorithm for Radar Signal Data Streams. [PDF]

Sensors (Basel)
Wan H, Lu C, Cui Y.
europepmc   +1 more source