Results 241 to 250 of about 242,385 (294)

H3K27 and H3K9 methylation mask potential CTCF binding sites to maintain 3D genome integrity. [PDF]

Genome Res
Fukuda K, Shimura C, Shinkai Y.
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Gut microbiota shape diurnal rhythms of amino acid metabolism in the mouse prefrontal cortex. [PDF]

Mol Metab
Tofani GSS, Cryan JF.
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Temporal dynamics and functional annotation of transcriptome rhythmicity in HEK293T cells. [PDF]

PLoS One
Sun Y, Dong H, Ge F, Zhao Y, Yang S, Ding Y, Dong M, Wang L, Zhang T.   +8 more
europepmc   +1 more source

Comparative RNA-Seq Analysis of Colon Spheroids and Patient-derived Tissues Identifies Non-Canonical Transcript Isoforms of Protein-Coding Genes Implicated in Colon Carcinogenesis. [PDF]

Cancer Inform
Babic T, Banovic Djeri B, Pavlovic D, Dragicevic S, Despotovic J, Karanovic J, Nikolic A.   +6 more
europepmc   +1 more source

Transposable Elements Regulate Tail Development and Fat Deposition in Sheep Fetuses. [PDF]

Animals (Basel)
Liang Q, Yang H, Dong H, Andersson G, Bongcam-Rudloff E, Wan P, Turganbekovich Kulatayev B, Rouzi M, Yang M, Han J.   +9 more
europepmc   +1 more source

A Case Report on a Challenge From Diagnosis to Treatment: Interstitial Lung Disease As the First Manifestation of Systemic Sclerosis Sine Scleroderma. [PDF]

Cureus
Viana S, Sá Lima A, Guiomar V, Neves I, Môço R.   +4 more
europepmc   +1 more source