Spectral characterization of advanced glycation end products in human hemoglobin, serum albumin, and erythrocytes. [PDF]
Mondal S, Kamely N, Roy M, Dong CY.
europepmc +1 more source
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Comprehensive Evaluation of Gastrointestinal Factors Influencing the Stability and Function of mRNA-Encapsulated Lipid Nanoparticles. [PDF]
Shinkai T, Ogawa K, Mohamed MS, Ozeki T.
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Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
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Balanced crystalloid versus saline for resuscitation in adult sepsis: a systematic review and meta-analysis. [PDF]
Liu L, Cai B, He B.
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Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
A Dialogic Participatory Model Between Professionals and Patients for the Co-Creation of Transitioning Care Management Programmes in Rare Bone Diseases. [PDF]
Mordenti M +10 more
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The multifaceted roles of lysosomes in cancer
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
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Effect of Block Copolymer Architecture on Lead(II) Bromide (PbBr2) Dissociation and Complexation via Surface Adsorption in a Selective Solvent. [PDF]
Sun YS, Chen YC.
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A Quantum Annealing Approach for Solving Optimal Feature Selection and Next Release Problems. [PDF]
Zhang Y, Wang S, Yang W.
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