Results 41 to 50 of about 8,502,103 (299)

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Infinitely many solutions for a class of Kirchhoff-type equations

Open Mathematics
In this article, we consider a class of Kirchhoff-type equations: −a+b∫Ω∣∇u∣2dxΔu=f(x,u),x∈Ω,u=0,x∈∂Ω.\left\{\begin{array}{ll}-\left(a+b\mathop{\displaystyle \int }\limits_{\Omega }{| \nabla u| }^{2}{\rm{d}}x\right)\Delta u=f\left(x,u),\hspace{1.0em}& x ...
Zhou Qin, Zeng Jing
doaj   +1 more source

On a problem for a system of two the second order differential equations via the theory of vector fields

Nonlinear Analysis, 2015
We consider Dirichlet boundary value problem for systems of two second-order differential equations with nonlinear continuous and bounded functions in right-hand sides. We prove the existence of a nontrivial solution to the problem comparing behaviors of
Inara Yermachenko, Felix Sadyrbaev
doaj   +1 more source

The Solution to Multiple Structures [PDF]

Structure, 2008
Getting high-resolution structures of large proteins in solution has always been a challenge. In this issue of Structure, Krukenberg et al. have used new methods of analyzing SAXS data to reveal a novel conformation of Hsp90 in solution.
openaire   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

Redefining Healthcare Infrastructure: Moving Toward Integrated Solutions [PDF]

, 2010
Currently in the United Kingdom there is a trend to broaden the scope of service provision in the healthcare sector. Not only are new healthcare-related services being provided to the community, but also there is increasing concern for providing ...
Formoso, Carlos Torres, Tillmann, P, Formoso, C, Tillmann, Patricia, Tzortzopoulos, Patricia, Tzortzopoulos, P   +5 more
core   +2 more sources

Multiple positive solutions for a class of concave-convex Schrödinger-Poisson-Slater equations with critical exponent

Advances in Nonlinear Analysis
In this article, we consider the multiplicity of positive solutions for a static Schrödinger-Poisson-Slater equation of the type −Δu+u2∗1∣4πx∣u=μf(x)∣u∣p−2u+g(x)∣u∣4uinR3,-\Delta u+\left({u}^{2}\ast \frac{1}{| 4\pi x| }\right)u=\mu f\left(x){| u| }^{p-2 ...
Zheng Tian-Tian, Lei Chun-Yu, Liao Jia-Feng   +2 more
doaj   +1 more source

Geode-Numerics

, 2023
Numerics proprietary Geode-solutions OpenGeode ...
Geode-solutions
core   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Multiple solutions for systems of multi-point boundary value problems [PDF]

Opuscula Mathematica, 2013
In this paper, we establish the existence of at least three solutions of the multi-point boundary value system \[\left\{\begin{array}{ll} -(\phi_{p_i}(u'_{i}))'=\lambda F_{u_{i}}(x,u_{1},\ldots,u_{n}),\ t\in(0,1),\\ u_{i}(0)=\sum_{j=1}^m a_ju_i(x_j ...
John R. Graef, Shapour Heidarkhani, Lingju Kong   +2 more
doaj   +1 more source