Results 11 to 20 of about 215,820 (253)

Cognitive Impairments in Multiple System Atrophy of the Cerebellar Type [PDF]

Journal of Movement Disorders, 2011
Background and Purpose We investigated the cognitive profiles in a large sample of patients with multiple system atrophy-cerebellar ataxia (MSA-C) and compared directly them in patients with clinical diagnosis of probable MSA-C without dementia and ...
Hyun J. Hong, Sook Keun. Song, Phil Hyu Lee, Young Ho Sohn, Ji E. Lee   +4 more
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Identification of microRNAs for the early diagnosis of Parkinson’s disease and multiple system atrophy [PDF]

Journal of Integrative Neuroscience, 2020
MicroRNAs are reportedly involved in the pathogenesis of neurodegenerative diseases, including Parkinson’s disease and multiple system atrophy. We previously identified 7 differentially expressed microRNAs in Parkinson’s disease patients and control sera
Jia-Hui Yan, Ping Hua, Yong Chen, Lan-Ting Li, Cui-Yu Yu, Lei Yan, Hui Zhang, Ying He, Hao Zheng, Hui Chen, Zhao-Jing Zhang, Qi-Hui Yao, Hui Dong, Wei-Guo Liu
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Gustatory rhinitis in multiple system atrophy

Acta Oto-Laryngologica Case Reports, 2021
Gustatory rhinitis is a type of nonallergic, noninflammatory rhinitis. A high incidence of rhinorrhea, including gustatory rhinitis, is reported in patients with Parkinson’s disease (PD). Herein, we report a case of gustatory rhinitis in a patient with a
Kaoru Yamakawa, Kenji Kondo, Akihiko Unaki, Hideto Saigusa, Kyohei Horikiri, Tatsuya Yamasoba   +5 more
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Multiple system atrophy [PDF]

, 2019
Multiple system atrophy (MSA) is a sporadic, adult-onset, relentlessly progressive neurodegenerative disorder, clinically characterized by various combinations of autonomic failure, parkinsonism and ataxia. The neuropathological hallmark of MSA are glial cytoplasmic inclusions consisting of misfolded α-synuclein.
Fanciulli, Alessandra, Stankovic, Iva, Krismer, Florian, Seppi, Klaus, Levin, Johannes, Wenning, Gregor K.   +5 more
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Freezing of Gait in Multiple System Atrophy

Frontiers in Aging Neuroscience, 2022
Background and PurposeFreezing of gait (FOG) is a common gait disturbance phenomenon in multiple system atrophy (MSA) patients. The current investigation assessed the incidence FOG in a cross-sectional clinical study, and clinical correlations associated
Huaguang Yang, Weiyin Vivian Liu, Shanshan Wang, Wenbin Yang, Changsheng Liu, Zhi Wen, Lanhua Hu, Jinxia Guo, Guoguang Fan, Xiaoguang Luo, Yunfei Zha   +10 more
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Multiple system atrophy - a clinicopathological update

Free Neuropathology, 2020
Multiple system atrophy (MSA) is a fatal, adult-onset neurodegenerative disorder of uncertain etiology, clinically characterized by various combinations of Levo-dopa-unresponsive parkinsonism, and cerebellar, motor, and autonomic dysfunctions.
Kurt A. Jellinger
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Heterogeneity of Multiple System Atrophy: An Update

Biomedicines, 2022
Multiple system atrophy (MSA) is a fatal, rapidly progressing neurodegenerative disease of uncertain etiology, clinically characterized by various combinations of Levodopa unresponsive parkinsonism, cerebellar, autonomic and motor dysfunctions.
Kurt A. Jellinger
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Models of multiple system atrophy [PDF]

Experimental & Molecular Medicine, 2019
AbstractMultiple system atrophy (MSA) is a neurodegenerative disease with diverse clinical manifestations, including parkinsonism, cerebellar syndrome, and autonomic failure. Pathologically, MSA is characterized by glial cytoplasmic inclusions in oligodendrocytes, which contain fibrillary forms of α-synuclein.
Lee, He-Jin, Ricarte, Diadem, Ortiz, Darlene, Lee, Seung-Jae   +3 more
openaire   +2 more sources

Dystonia in multiple system atrophy [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 2002
To delineate the frequency and nature of dystonia in multiple system atrophy (MSA).A cohort of 24 patients with clinically probable MSA over the past 10 years were prospectively followed up. Motor features were either dominated by parkinsonism (MSA-P subtype, n=18) or cerebellar ataxia (MSA-C, n=6). Classification of dystonic features and their changes
S M, Boesch, G K, Wenning, G, Ransmayr, W, Poewe   +3 more
openaire   +2 more sources

The genetic basis of multiple system atrophy

Journal of Translational Medicine, 2023
Multiple system atrophy (MSA) is a heterogenous, uniformly fatal neurodegenerative ɑ-synucleinopathy. Patients present with varying degrees of dysautonomia, parkinsonism, cerebellar dysfunction, and corticospinal degeneration.
Fan Shuen Tseng, Joel Qi Xuan Foo, Aaron Shengting Mai, Eng-King Tan   +3 more
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