Characterizing the impact of incorporating spatially aggregated human mobility data into infectious disease models. [PDF]
Corgel R +8 more
europepmc +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Sustained resilience as a unifying property of cities and the built environment. [PDF]
Mitoulis SA +3 more
europepmc +1 more source
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Powering Neurology Drug Development Trials to Reduce False Negative Results. [PDF]
Mori H +3 more
europepmc +1 more source
ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley +5 more
wiley +1 more source
Scale-dependent biases in systematic land cover maps undermine freshwater ecological assessment. [PDF]
Fernández de Larrea I +3 more
europepmc +1 more source
Theory and practice in biomedical informatics: a framework for discovery. [PDF]
Stead WW +4 more
europepmc +1 more source
Self-report Instruments for Anxiety, Depression, and Stress in Adolescents: A Scoping Review of Psychometric Properties and Cultural Applicability. [PDF]
Srivastava D, Mahanta D.
europepmc +1 more source
Innovative assessment of meteorological drought in northern Algeria using the NIFT index. [PDF]
Zerouali B +6 more
europepmc +1 more source

