Current Concepts in Orthopedic Management of Multiple Trauma
The Open Orthopaedics Journal, 2015 Multiple trauma patients frequently present challenging clinical scenarios with musculoskeletal injuries being the most common indications for surgical procedures in these patients.
F. Kucukdurmaz, P. Alijanipour
semanticscholar +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Evaluation of MGAP and GAP Trauma Scores to Predict Prognosis of Multiple-trauma Patients
, 2016 Background: Early diagnosis of major trauma and rapid transmission of patients to appropriate therapeutic centers have always been issues of concern.
F. Rahmani +4 more
semanticscholar +1 more source
Less is more? Assessing the validity of the ICD-11 model of PTSD across multiple trauma samples
European Journal of Psychotraumatology, 2015 Background In the 5th edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), the symptom profile of posttraumatic stress disorder (PTSD) was expanded to include 20 symptoms.
Maj Hansen +4 more
semanticscholar +1 more source
Computational evidence for an early, amplified systemic inflammation program in polytrauma patients with severe extremity injuries [PDF]
, 2019 Extremity and soft tissue injuries contribute significantly to inflammation and adverse in-hospital outcomes for trauma survivors; accordingly, we examined the complex association between clinical outcomes inflammatory responses in this setting using in ...
Abboud, Andrew +10 more
core +3 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The Relationship Between Community Violence and Trauma: How Violence Affects Learning, Health, and Behavior [PDF]
, 2017 Research on trauma is frequently featured in mainstream news outlets, pointing to its connection to a range of behavioral and health outcomes. While trauma can have multiple interpretations, for the purposes of this report, it is the result of ...
Jennifer Lynn-Whaley, Josh Sugarmann
core
Trauma characteristics and posttraumatic growth: The mediating role of avoidance coping, intrusive thoughts and social support [PDF]
, 2019 Objective: Previous research suggests trauma characteristics can impact on posttraumatic growth (PTG). The current study considers whether previously identified predictors of PTG may produce different outcomes dependent on the characteristics of the ...
Brooks, Matthew +3 more
core +3 more sources
Prehospital critical care is associated with increased survival in adult trauma patients in Scotland [PDF]
, 2020 Background Scotland has three prehospital critical care teams (PHCCTs) providing enhanced care support to a usually paramedic-delivered ambulance service.
Carr, David +7 more
core +3 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source