Results 241 to 250 of about 592,190 (345)

A Human Kidney Tubuloid Model of Repeated Cisplatin‐Induced Cellular Senescence and Fibrosis for Drug Screening

Advanced Healthcare Materials, EarlyView.
Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).
Yuki Nakao, Makiko Mori, Yuta Sekiguchi, Iori Morita, Ryota Shindoh, Shintaro Mandai, Tamami Fujiki, Hiroaki Kikuchi, Fumiaki Ando, Koichiro Susa, Takayasu Mori, Ayumi Suzuki, Yuji Nashimoto, Hirokazu Kaji, Yuma Waseda, Soichiro Yoshida, Yasuhisa Fujii, Eisei Sohara, Shinichi Uchida, Kensuke Miyake, Yutaro Mori   +20 more
wiley   +1 more source

Modular Platform for Rapidly Investigating Long‐Distance Propagation of Human Neural Network Activity

Advanced Healthcare Materials, EarlyView.
This study presents the first human neural organoid culture model capable of rapidly exhibiting long‐distance neural network propagation, thus delivering a system to experimentally investigate large‐scale communication during normal and diseased states.
Megh Dipak Patel, Sailee Sham Lavekar, Ronak Jaisalmeria, Suki Oji, Jazmine Jayasi, Caroline Cvetkovic, Robert Krencik   +6 more
wiley   +1 more source

A Novel Microfluidic System for 3D Epidermis and Full‐Thickness Skin Growth for Nanoparticle Safety Assessment

Advanced Healthcare Materials, EarlyView.
This work presents a novel, dynamically perfused, configurable microfluidic system for epidermis‐only (E and full‐thickness skin (FT SoC) growth, emulating human skin structure and barrier function. Upon TiO2 nanoparticle exposure, the system reveals compromised barrier integrity, reduced metabolic activity, increased permeability, and chemokine‐driven
Samantha Costa, Ana B. Carneiro, Filipa Lebre, João Meneses, Alar Ainla, Cacilda Moura, Ernesto Alfaro‐Moreno, Ana R. Ribeiro   +7 more
wiley   +1 more source

Development and application of a multiplex TaqMan real-time PCR assay for detecting pathogenic fungi causing root rot in red kidney bean. [PDF]

Front Plant Sci
Liu W, Peng X, Li H, Kang H, Zhao J, Yang C, Zhao X, Hao X.   +7 more
europepmc   +1 more source

A roadmap of osteogenic differentiation in human mesenchymal stem cells assessed by protein multiplex analysis

Maria Eischen‐Loges, Zeinab Tahmasebi Birgani, Yousra Alaoui Selsouli, Lars Eijssen, Hoon Suk Rho, Mireille M.J.P.E. Sthijns, Martijn van Griensven, Vanessa L.S. LaPointe, Pamela Habibović   +8 more
openalex   +1 more source

Optimizing laser coupling, matter heating, and particle acceleration from solids using multiplexed ultraintense lasers [PDF]

W. Yao, M. Nakatsutsumi, S. Buffechoux, P. Antici, M. Borghesi, A. Ciardi, S. N. Chen, E. d’Humières, L. Grémillet, R. Heathcote, Vojtěch Horný, P. McKenna, M. N. Quinn, L. Romagnani, Ryan Royle, G. Sarri, Y. Sentoku, Hans-Peter Schlenvoigt, T. Toncian, O. Tresca, L. Vassura, Oswald Willi, J. Fuchs   +22 more
openalex   +1 more source

After Liberal Hegemony: The Advent of a Multiplex World Order*

Ethics & International Affairs, 2017
Amitav Acharya
semanticscholar   +1 more source

Fluorescent Polymeric Nanofibers as Ratiometric Multiplexed Skin Sensors of pH and Oxygen

Advanced Healthcare Materials, EarlyView.
Fluorescent polymeric nanofibers and nanorods are produced as ratiometric sensors of two important physiological parameters: pH and oxygen. They operate by dual Forster resonance energy transfer from large number of energy donor dyes to limited number of two distinct energy acceptors, enabling simultaneous sensing of pH and oxygen.
Rémi Pelletier, Anila Hoskere Ashoka, Andrey S. Klymchenko   +2 more
wiley   +1 more source

Numerical analysis and design of polarization-multiplexing modulator utilizing the epsilon-near-zero behavior in ITO-HfO2-graphene stacked layers

Xingxin Fan, Yanhua Shen, Zhiyu Chen, Rongguo Lu, Daolong Shi, Xin Wei, Yong Liu   +6 more
openalex   +2 more sources

Spherical Skin Model: Stratified Co‐Culture of Fibroblasts and Keratinocytes on Spherical Beads Toward Compound Screening

Advanced Healthcare Materials, EarlyView.
Models of the human skin must combine the relevant biological contents and suitable biomaterials with the correct spatial organization. Performing compound screening on such in vitro models also requires fast and reproducible production methods of the models.
Elisa Lenzi, Nadia Vertti‐Quintero, Julien Husson, Anne‐Laure Bulteau, Carine Nizard, Karl Pays, Sébastien Sart, Charles N. Baroud   +7 more
wiley   +1 more source