Results 61 to 70 of about 539,280 (316)

Towards real-world complexity: an introduction to multiplex networks

open access: yes, 2015
Many real-world complex systems are best modeled by multiplex networks of interacting network layers. The multiplex network study is one of the newest and hottest themes in the statistical physics of complex networks.
Goh, Kwang-Il   +2 more
core   +1 more source

Multiplex Immunoassay and Bead Based Multiplex [PDF]

open access: yes, 2012
Protein immunoassays provide information about quantities and forms of endogenous proteins. Uniplex enzyme immunoassays like Elisa have been the workhorse for protein measurement for decades, but they can be laborious and expensive and consume relatively large amounts of specimen.
openaire   +3 more sources

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

The New and the Old: Platform Cross-Validation of Immunoaffinity MASS Spectrometry versus ELISA for PromarkerD, a Predictive Test for Diabetic Kidney Disease

open access: yesProteomes, 2020
PromarkerD is a proteomics derived test for predicting diabetic kidney disease that measures the concentrations of three plasma protein biomarkers, APOA4, CD5L and IBP3.
Scott Bringans   +4 more
doaj   +1 more source

Unique superdiffusion induced by directionality in multiplex networks

open access: yesNew Journal of Physics, 2021
The multilayer network framework has served to describe and uncover a number of novel and unforeseen physical behaviors and regimes in interacting complex systems.
Xiangrong Wang   +3 more
doaj   +1 more source

Graphlets in Multiplex Networks [PDF]

open access: yesScientific Reports, 2020
AbstractWe develop graphlet analysis for multiplex networks and discuss how this analysis can be extended to multilayer and multilevel networks as well as to graphs with node and/or link categorical attributes. The analysis has been adapted for two typical examples of multiplexes: economic trade data represented as a 957-plex network and 75 social ...
Kristijan Petrovski   +3 more
openaire   +3 more sources

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

Design and Evaluation of a Novel Multiplex Real-Time PCR Melting Curve Assay for the Simultaneous Detection of Nine Sexually Transmitted Disease Pathogens in Genitourinary Secretions

open access: yesFrontiers in Cellular and Infection Microbiology, 2019
Background: Sexually transmitted diseases (STD) are a major cause of infertility, long-term disability, ectopic pregnancy, and premature birth. Therefore, the development of fast and low-cost laboratory STD diagnostic screening methods will contribute to
Xiao-Mei Hu   +16 more
doaj   +1 more source

SARSPLEX: Multiplex Serological ELISA with a Holistic Approach

open access: yesViruses, 2022
Currently, there are over 602 million severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cases and 6.4 million COVID-19 disease-related deaths worldwide.
Kunal Garg   +6 more
doaj   +1 more source

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