Results 281 to 290 of about 465,638 (353)

ANGPT2 Drives Thyroid Cancer Progression Through PI3K/AKT Signaling and Correlates With Poor Prognosis and Immune Infiltration

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Angiopoietin‐2 (ANGPT2) is known to participate in tumor progression and immune modulation across multiple malignancies. Nevertheless, its expression pattern, prognostic value, and biological function in thyroid cancer (THCA) have not been comprehensively investigated.
Han Chen   +5 more
wiley   +1 more source

Dietary resilience of coral reef fishes to habitat degradation

open access: yesJournal of Animal Ecology, EarlyView.
Metabarcoding of gut contents shows that two common benthic‐feeding reef fishes with different feeding stratgies—a butterflyfish (Chaetodon capistratus) and a hamlet (Hypoplectrus puella)—shift diets on degraded reefs. These shifts mirror contrasting patterns in body condition: butterflyfish showed strong individual variation, whereas condition was ...
Friederike Clever   +9 more
wiley   +1 more source

DNA‐Methylation for Risk‐Stratification of Women Without a Fully Visible Transformation Zone at Colposcopy: A Cross‐Sectional Study

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To evaluate the performance of DNA methylation markers for the detection of cervical precancer among screening‐positive older women without a fully visible transformation zone at colposcopy (TZ3). Design Cross‐sectional study. Setting Colposcopy clinics, Central Denmark Region, 2019–2021.
Karen Omann Binderup   +10 more
wiley   +1 more source

Understanding biological control function and trophic interaction dynamics of an artificially released predatory bug by DNA metabarcoding

open access: yesInsect Science, EarlyView.
This study investigated the dietary composition of Sycanus bifidus, a generalist predator of the assassin bug that is artificially released into citrus orchards, and uncovered its trophic structure across various pest species using metabarcoding‐based molecular gut content analysis.
Weidong Huang   +9 more
wiley   +1 more source

Acetylcholine From Solitary Chemosensory Cell, Not Neuron, Regulates Basal Cell Fate Driving Eosinophilic Chronic Rhinosinusitis With Nasal Polyps

open access: yesAllergy, EarlyView.
This study identifies that Ach levels are elevated in eCRSwNP and primarily released from SCCs rather than neurons. Ach induces epithelial remodeling in eCRSwNP by binding to M1R/M3R and activating YAP signaling in basal cells, driving basal cell hyperplasia and abnormal differentiation. Blocking M1R/M3R with TB inhibits eCRSwNP progression.
Bowen Zheng   +20 more
wiley   +1 more source

Protective Role for Itaconate During Inhaled Allergen Challenge

open access: yesAllergy, EarlyView.
Itaconate levels decrease in sputum following allergen inhalation in mild asthmatics, suggesting a dynamic metabolic response to airway challenge. Genetic deletion of Acod1 in mice did not alter airway inflammation or remodelling in response to chronic HDM exposure.
Gesa J. Albers   +16 more
wiley   +1 more source

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