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The Therapeutic Potential of Farm Dust Extracts in a Mouse Model of Eosinophilic Inflammation
Farm dust extract (FDE) treatment reduces airway eosinophilia, mucus overproduction, and MHC‐II expression on DCs, limiting antigen presentation and Th2 inflammation. It increases PD‐L1 on DCs, promoting T cell deactivation. Additionally, FDE enhances Tregs and upregulates CTLA‐4, reinforcing suppression.
Rabia Ülkü Korkmaz +16 more
wiley +1 more source
Cryptorchidism: Novel genetic insights into CCDC149 mutations
Abstract Background Cryptorchidism, characterized by the failure of one or both testes to descend into the scrotum, is a common congenital condition that can lead to infertility and increased risk of testicular cancer. CCDC149, a coiled‐coil domain‐containing protein, has been implicated in various developmental processes, but its role in the male ...
Shengrong Du +8 more
wiley +1 more source
Optimized Antibiotic Management of Critically Ill Patients with Severe Pneumonia Following Multiplex Polymerase Chain Reaction Testing: A Prospective Clinical Exploratory Trial. [PDF]
Verroken A +5 more
europepmc +1 more source
Multiplex polymerase chain reaction assay for genotyping Clostridium perfringens
Abstract Objective To develop a multiplex polymerase chain reaction (PCR) assay to detect the genes for the major toxins of Clostridium perfringens (cpa [α toxin], cpb [β toxin], etx [ε toxin], iA [ι i toxin], and cpe [enterotoxin]). Sample Population Cultures of C perfringens obtained from collections and diagnosticians throughout North America ...
R R, Meer, J G, Songer
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Assembled Step Emulsification Device for Multiplex Droplet Digital Polymerase Chain Reaction
Analytical Chemistry, 2019Digital PCR is a powerful method for absolute nucleic acid quantification with unprecedented accuracy and precision. To promote the wider use and application of digital PCR, several major challenges still exist, including reduction of cost, integration of the instrumental platform, and simplification of operations.
Mengyue Nie +9 more
openaire +3 more sources

