Results 181 to 190 of about 1,907,812 (295)

Expansion microscopy using a single anchor molecule for high-yield multiplexed imaging of proteins and RNAs. [PDF]

PLoS One, 2023
Cui Y, Yang G, Goodwin DR, O'Flanagan CH, Sinha A, Zhang C, Kitko KE, Shin TW, Park D, Aparicio S, CRUK IMAXT Grand Challenge Consortium, Boyden ES.   +11 more
europepmc   +1 more source

Controllable Cascade Aggregation Ion Programmed Nanomachines and Simple Isolation Enable Tumor‐Derived Small Extracellular Vesicles Detection for Enhanced Breast Cancer Assessment

Advanced Science, EarlyView.
This study developed a convenient, enzyme‐free detection platform based on controllable aggregation ion nanomachines. Its favorable anti‐interference capacity and high sensitivity meet the detection requirements for clinical samples processed via a simple filtration method within 10 min.
Zhihao Zhang, Zijing Liu, Xiangyue Meng, Pengjun Jiang, Jie Qu, Yu Jiang, Binxu Qiu, Jie Chen, Piaopiao Chen   +8 more
wiley   +1 more source

Deep immune profiling of intrahepatic cholangiocarcinoma with CODEX multiplexed imaging. [PDF]

Hepatol Commun
Baretti M, Shekhar S, Sahai V, Shu D, Howe K, Gunchick V, Assarzadegan N, Kartalia E, Zhu Q, Hallab E, Sheth-Shah A, Kondo A, Azad NS, Yarchoan M.   +13 more
europepmc   +1 more source

Optimizing multiplexed imaging experimental design through tissue spatial segregation estimation. [PDF]

Nat Methods, 2023
Bost P, Schulz D, Engler S, Wasserfall C, Bodenmiller B.   +4 more
europepmc   +1 more source

EBV‐Driven ODC1 Upregulation Enhances Polyamine Anabolism to Promote Viral Replication and Cisplatin Resistance in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
EBV‑BZLF1 initiates ODC1‑driven polyamine anabolism that correlates with poor clinical prognosis in nasopharyngeal carcinoma. The ODC1–spermidine axis promotes viral replication, cell proliferation and innate immune evasion. Pharmacological inhibition of ODC1 rescues cisplatin sensitivity, establishing ODC1 as a viable therapeutic target for EBV ...
Yueshuo Li, Xudong Hu, Chenxing Yang, Na Liu, Lin Wang, Xi Cai, Min Tang, Ya Cao, Li Shang, Feng Shi   +9 more
wiley   +1 more source

Protocol for spatial proteomic profiling of tonsil cancer microenvironments using multiplexed imaging-powered deep visual proteomics. [PDF]

STAR Protoc
Zheng X, Mund A, Mann M.
europepmc   +1 more source

mxnorm: An R Package to Normalize Multiplexed Imaging Data. [PDF]

J Open Source Softw, 2022
Harris C, Wrobel J, Vandekar S.
europepmc   +1 more source

Transparent Topological Meta‐Diplexer via Tightly Confined Valley Surface States

Advanced Science, EarlyView.
An optically transparent topological metasurface supporting tightly confined valley surface states enables robust and flexible wave routing in an ultrathin platform. A compact transparent meta‐diplexer with spatially and spectrally separated channels is realized, while communication experiments verify high‐fidelity signal transmission, opening new ...
Sijie Li, Ping Li, Zhihao Lan, Yin Li, Hang Wong, Menglin L.N. Chen   +5 more
wiley   +1 more source

Single‐Dose TACE‐Like Injection of Sustained‐Release Panobinostat/IL‐12 Polymeric Microparticles is Effective in Preclinical Liver Cancer Models

Advanced Science, EarlyView.
A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu, Ling Li, Sachin S. Surwase, Xin Ming M. Zhou, Hongtao Qian, Joel C. Sunshine, Florin M. Selaru, Jordan J. Green   +7 more
wiley   +1 more source

Multiplexed imaging mass cytometry elicits p-S6 as a therapeutic and prognostic factor in diffuse large B-cell lymphoma. [PDF]

Blood Adv
Zhang B, Xie Y, Shen M, Sun J, Li Y, Zhang J, Li Q, Chen C, Chen Z, Wang W, Wu J, Zhou Z, Fang J, Yan Y, Qian S, Tong X, Lin N, Tong H.   +17 more
europepmc   +1 more source