Results 41 to 50 of about 88,556 (313)

Multiplexity and multireciprocity in directed multiplexes

Physical Review E, 2016
20 pages, 8 ...
Gemmetto, V., Squartini, T., Picciolo, F., Ruzzenenti, F., Garlaschelli, D.   +4 more
openaire   +6 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

On-Chip Silicon Two-Mode (De)Multiplexer for OFDM/OQAM Data Transmission Based on Grating-Assisted Coupler

IEEE Photonics Journal, 2015
We fabricate and demonstrate on-chip two-mode (de)multiplexing using a tapered asymmetrical grating-assisted contradirectional coupler-based TE0 and TE2 mode multiplexer and demultiplexer on the silicon-on-insulator platform.
Chengcheng Gui, Ya Gao, Zhonglai Zhang, Jian Wang   +3 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Analysis and Synthesis of Single-Bit Adders for Multi-Bit Adders with Sequential Transfers

Engineering Proceedings
This paper provides an analysis of existing single-digit binary adders from the point of view of their implementation on fans built based on metal-oxide-semiconductor field-effect transistor—MOSFETs.
Sakhybay Tynymbayev, Assel Mukasheva, Kuanyshbek Ibragimov, Adil Mukhamedgali, Gani Sergazin, Teodor Iliev   +5 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Multiplexed Supply of a MISO Wireless Power Transfer System for Battery-Free Wireless Sensors

Energies, 2020
Multi-input single output wireless power transmission (MISO-WPT) systems have decisive advantages concerning flexible receiver position in comparison to single coil systems.
Ghada Bouattour, Mohamed Elhawy, Slim Naifar, Christian Viehweger, Houda Ben Jmaa Derbel, Olfa Kanoun   +5 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Comparison of AWGs and Echelle Gratings for Wavelength Division Multiplexing on Silicon-on-Insulator

IEEE Photonics Journal, 2014
We compare the performance (insertion loss and crosstalk) of silicon-based arrayed waveguide gratings (AWGs) and echelle gratings for different channel spacings.
S. Pathak, P. Dumon, D. Van Thourhout, W. Bogaerts   +3 more
doaj   +1 more source

Design and simulation of high-performance 2:1 multiplexer based on side-contacted FED

Ain Shams Engineering Journal, 2021
Designing a high-quality switch block ensures the efficient data transmission in digital circuits and systems. In this paper, an innovative 2:1 multiplexer is successfully designed based on the previously proposed side-contacted field-effect diodes (S ...
Tara Ghafouri, Negin Manavizadeh
doaj   +1 more source