Results 251 to 260 of about 105,146 (314)

Computational epitope heterogeneity analysis in immunostainings from antibody-dilution series. [PDF]

Commun Biol
Tschimmel D, Saeed M, Milani M, Waldherr S, Hucho T.   +4 more
europepmc   +1 more source

Hadamard Matrix Slicing Single‐Pixel Imaging: Establishing a Linear‐Array‐Inspired Paradigm for N‐fold Acceleration Single‐Pixel Imaging

Advanced Science, EarlyView.
To overcome two‐dimensional modulation bottlenecks, Hadamard Matrix Slicing Single‐Pixel Imaging (HMS‐SPI) establishes an efficient one‐dimensional imaging paradigm. By slicing the traditional Hadamard matrix into one‐dimensional encoding vectors and spatially expanding them, the required measurement patterns decrease by a factor of N.
Xiaoxue Li, Jieting Hou, Qizheng Zhao, Yiqi Jia, Xiang Zhong, Mengchao Ma, Huaxia Deng, Xinglong Gong, Ziwei Wang   +8 more
wiley   +1 more source

Diffractive magic cube network with super-high capacity enabled by mechanical reconfiguration. [PDF]

Nat Commun
Feng P, Liu F, Liu Y, Chong M, Zhang Z, Zhao Q, Li J, Pan R, Wang Z, Sun J, Zhou J, Tan Y.   +11 more
europepmc   +1 more source

PANX2 Suppresses Lung Adenocarcinoma Progression by Inducing Disulfidptosis and Enhancing Antitumor Immunity

Advanced Science, EarlyView.
ABSTRACT Lung adenocarcinoma (LUAD) remains a leading cause of cancer mortality with limited therapeutic options. Disulfidptosis, a novel cell death modality driven by disulfide stress, represents a promising target, yet its regulation in LUAD is poorly defined. Here, we identify Pannexin 2 (PANX2) as a tumor suppressor in LUAD.
Yi Chen, Zhao‐Yu Liu, Gao‐Wen Qu, Run‐Hao Zeng, Wen‐Xia Yao, Yong‐Bing Zhou, Xue Liang, Yu‐Xiong Lai   +7 more
wiley   +1 more source

Tumor‐Infiltrating mregDCs Restrain Anti‐Tumor Immunity in Early Relapse HCC

Advanced Science, EarlyView.
Tumor‐infiltrating mregDCs are regulated by the TNFR2‐non‐canonical NF‐κB axis, which is mediated by TNF‐α secreted by CD161+CD8+ T cells. These mregDCs recruit CD161+CD8+ T cells via the CCL20‐CCR6 axis, forming a positive feedback loop that enhances immunosuppression, promotes early recurrence of HCC, and further confirms TNFR2 as a key therapeutic ...
Zefan Zhang, Lin Ding, Yu Zhong, Haokang Feng, Linglong Huang, Waidong Huang, Chunqing Wang, Arne Östman, Beili Wang, Jian Zhou, Jia Fan, Wei Guo, Liang Wu, Yunfan Sun   +13 more
wiley   +1 more source

Metropolitan-scale ion-photon entanglement via a quantum network node with hybrid multiplexing enhancements. [PDF]

Nat Commun
Cui ZB, Wang ZQ, Lai PC, Wang Y, Shi JX, Liu PY, Sun YD, Tian ZC, Liang YB, Qi BX, Huang YY, Zhou ZC, Wu YK, Xu Y, Duan LM, Pu YF.   +15 more
europepmc   +1 more source

Compact Tabletop Magnetic Resonance Elastography for Mapping Soft Tissue Viscoelasticity

Advanced Science, EarlyView.
This work introduces a compact, low‐cost tabletop magnetic resonance elastography platform for high‐resolution viscoelastic mapping in soft‐tissue specimens. Using this method in human colorectal liver metastases, we demonstrate fully automated biomechanical profiling of treatment response and show that heterogeneity‐based metrics outperform ...
Weijie Zhao, Lisa‐Marie Skrip, Heiko Tzschätzsch, Tom Meyer, Hossein S. Aghamiry, Alexander Arnold, Lene Änne Böhne, Jakob Jordan, Oliver Boehm, Agnes K. Boehm, Steffen Görner, Jakob Schattenfroh, Yanglei Wu, Pedro Augusto Dantas de Moraes, Johann Pratschke, Jürgen Braun, Igor M. Sauer, Jing Guo, Ingolf Sack, Karl H. Hillebrandt   +19 more
wiley   +1 more source

Single-Cell Proteomic Technologies: Tools in the Quest for Principles. [PDF]

Annu Rev Biophys
Slavov N.
europepmc   +1 more source

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiubei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hongli Jiao   +11 more
wiley   +1 more source

Ultra-wideband optical diffractive network for mode multiplexing across the entire telecommunication range. [PDF]

Nat Commun
Kong A, Ren J, Wang K, Yu Y, Lin R, Wang C, Long J, Pang F, Chen X, Yan X, Wang Z, Liu B, Lei T, Yuan X.   +13 more
europepmc   +1 more source