Results 321 to 330 of about 539,225 (413)

Three‐Channel Wavefront Shaping Using Non‐Interleaved Spin‐Multiplexed Plasmonic Metasurfaces

open access: yesAdvanced Science, EarlyView.
A versatile non‐interleaved plasmonic metasurface platform has been developed using quarter‐wave plate meta‐atoms for independent and simultaneous phase modulation of both co‐ and cross‐polarized circularly polarized waves. Three proof‐of‐concept designs have been validated in the near‐infrared: a beam deflector with three distinct reflection angles, a
Xingling Pan   +6 more
wiley   +1 more source

Prefrontal FGF1 Signaling is Required for Accumbal Deep Brain Stimulation Treatment of Addiction

open access: yesAdvanced Science, EarlyView.
This research delineates that a cortical‐accumbal pathway and local FGF1 signaling in the medial prefrontal cortex are critical for NAc‐DBS to be effective in altering morphine CPP. These findings demonstrate a top‐down motif to regulate the therapeutic effects of subcortical DBS on addiction and support the potential for addiction treatments involving
Wan‐Kun Gong   +11 more
wiley   +1 more source

PPY‐Induced iCAFs Cultivate an Immunosuppressive Microenvironment in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
Pancreatic ductal adenocarcinoma features abundant stromal components that hinder therapy efficacy. Single‐cell RNA sequencing analysis combined with experiments identified PPY, a gastrointestinal hormone, as a novel inducer of immunosuppressive iCAFs. Mechanistic studies revealed that PPY activates the non‐canonical NF‐κB pathway via EGFR.
Mengdie Cao   +14 more
wiley   +1 more source

Single‐Cell Atlas Reveals Tumorigenic Profiles and Immune Dynamics of Adrenal Incidentalomas

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA sequencing reveals cellular heterogeneity in adrenal incidentalomas, identifying distinct tumor cell populations. Clusterin is recognized as a biomarker for adrenocortical tumors, correlating with established markers. MYCN‐positive clusters in pheochromocytomas indicated poorer survival.
Meng Wang   +18 more
wiley   +1 more source

Corrigendum: A self-reference interference sensor based on coherence multiplexing. [PDF]

open access: yesFront Chem
Shen Y   +6 more
europepmc   +1 more source

4D Biofabrication of Magnetically Augmented Callus Assembloid Implants Enables Rapid Endochondral Ossification via Activation of Mechanosensitive Pathways

open access: yesAdvanced Science, EarlyView.
Magnetically augmented biohybrid cartilaginous microtissues enable remote microtissue motion control and assembly as well as targeted differentiation. This study demonstrates accelerated endochondral ossification under magnetic stimulation, highlighting cartilaginous assembloid constructs’ ability to retain long‐term magnetic properties.
Konstantinos Ioannidis   +13 more
wiley   +1 more source

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