Results 71 to 80 of about 184,412 (299)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Efficient Marker-Assisted Pyramiding of Xa21 and Xa23 Genes into Elite Rice Restorer Lines Confers Broad-Spectrum Resistance to Bacterial Blight

open access: yesPlants
Bacterial blight (BB) caused by Xanthomonas oryzae pv. oryzae (Xoo) is a major threat to global rice productivity. Although hybrid rice breeding has significantly enhanced yields, persistent genetic vulnerabilities within restorer lines continue to ...
Yao Li   +10 more
doaj   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Melatonin Improves Storage Quality of Sweetpotato (Ipomoea batatas) by Inhibiting Sprouting, Weight Loss, and Lignification and Elevating Sweetness

open access: yesPlants
It has been well established that exogenous melatonin (MT) improves storage quality of many agricultural products. However, contrasting results have been reported in the regulation of MT with respect to several postharvest parameters, e.g., germination ...
Jiawang Li   +3 more
doaj   +1 more source

Changes in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Inflammation is a critical risk factor for poor outcomes in cerebral infarction. Prior studies focused primarily on baseline inflammation status, neglecting dynamic longitudinal changes. We try to investigate the association between immune‐inflammation status alterations and stroke prognosis, and evaluated three systemic biomarkers'
Songfang Chen   +11 more
wiley   +1 more source

Volatilomics-Based Discovery of Key Volatiles Affecting Flavor Quality in Tomato

open access: yesFoods
Volatile accumulation during tomato ripening greatly affects the fruit flavor. In this study, four accessions from each of the three tomato subgroups (BIG, S. lycopersicum, CER, S. lycopersicumvar. Cerasiforme, and PIM, S.
Zhonghui Zhang   +9 more
doaj   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Green manuring improves soil quality, grain yield, and grain anthocyanin content in colored rice cultivated in tropical regions

open access: yesFood and Energy Security
Green manuring is the process by which vegetative crops are incorporated into the soil, and it plays a good substitutable role in reducing chemical fertilizer applications while enhancing soil fertility. Field experiments were conducted at Lingao City of
Shaokun Song   +7 more
doaj   +1 more source

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