Results 41 to 50 of about 10,538 (289)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Relative multiplication and distributive modules [PDF]

open access: yes, 1997
summary:We study the construction of new multiplication modules relative to a torsion theory $\tau $. As a consequence, $\tau $-finitely generated modules over a Dedekind domain are completely determined.
Torrecillas, Blas, Escoriza, José
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Diameter and girth of Torsion Graph

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2014
Let R be a commutative ring with identity. Let M be an R-module and T (M)* be the set of nonzero torsion elements. The set T(M)* makes up the vertices of the corresponding torsion graph, ΓR(M), with two distinct vertices x, y ∈ T(M)* forming an edge if ...
Rad P. Malakooti   +3 more
doaj   +1 more source

Some Properties of Multiplication Modules [PDF]

open access: yesJournal of the Indonesian Mathematical Society, 2017
Let M be an R-module. The module M is called multiplication if for anysubmodule N of M we have N = IM, where I is an ideal of R. In this paperwe state some basic properties of multiplication modules.
Tavallaee, Hamid A., Mahtabi, Robabeh
openaire   +2 more sources

Multiplication modules and related results [PDF]

open access: yes, 2004
summary:Let $R$ be a commutative ring with non-zero identity. Various properties of multiplication modules are considered. We generalize Ohm’s properties for submodules of a finitely generated faithful multiplication $R$-module (see [8], [12] and [3])
Ebrahimi Atani, Shahabaddin
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

On S-comultiplication modules

open access: yes, 2022
Let R be a commutative ring with 1 not equal 0 and M be an R-module. Suppose that S subset of R is a multiplicatively closed set of R. Recently Sevim et al.
TEKİR, ÜNSAL, KOÇ, SUAT
core   +2 more sources

Classification of multiplication modules over multiplication rings with finitely many minimal primes [PDF]

open access: yes, 2023
A classification of multiplication modules over multiplication rings with finitely many minimal primes is obtained. A characterisation of multiplication rings with finitely many minimal primes is given via faithful, Noetherian, distributive modules.
Bavula, Volodymyr
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy