Results 41 to 50 of about 402,850 (292)

Detection and Estimation of Abrupt Changes contaminated by Multiplicative Gaussian Noise [PDF]

open access: yes, 1998
The problem of abrupt change detection has received much attention in the literature. The Neyman Pearson detector can be derived and yields the well-known CUSUM algorithm, when the abrupt change is contaminated by an additive noise.
Jean-Yves Tourneret   +1 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

The development of multiplicative thinking in young children [PDF]

open access: yes, 2003
This paper describes developmental changes as children move from additive to multiplicative thinking. Five broad phases through which multiplicative thinking develops were synthesised from the research.
Jacob, L., Willis, S.
core  

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

open access: yesMolecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau   +9 more
wiley   +1 more source

On (anti-)multiplicative generalized derivations

open access: yesGlasnik matematički, 2012
Let R be a semiprime ring and let F, f : R → R be (not necessarily additive) maps satisfying F(xy)=F(x)y+xf(y) for all x,y R. Suppose that there are integers m and n such that F(uv)=mF(u)F(v)+nF(v)F(u) for all u, v in some nonzero ideal I of R. Under some mild assumptions on R, we prove that there exists c C(I⊥⊥) such that c=(m+n)c2, nc[I⊥⊥, I⊥⊥]=0 and
Eremita, Daniel, Ilisevic, Dijana
openaire   +6 more sources

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Curves in Multiplicative Equiaffine Space

open access: yesMathematics
In this study, the geometric properties of curves in multiplicative equiaffine space are investigated using multiplicative calculus. Fundamental geometric concepts such as multiplicative arc length, multiplicative equiaffine curvature, and torsion are ...
Meltem Ogrenmis, Alper Osman Ogrenmis
doaj   +1 more source

Soil characterization by near-infrared spectroscopy and principal component analysis

open access: yesRevista Ciência Agronômica, 2021
This research aimed to use principal component analysis (PCA) as an exploratory method for spectral data of soil absorbance from the Baturité Massif and Central Hinterland (Ceará State, Brazil) to verify the potential of the technique in soil ...
Maria Ivanilda de Aguiar   +3 more
doaj   +1 more source

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