ABSTRACT The review examines the evolution of chemical ionization mass spectrometry (CI‐MS), a technique developed in 1966 by Field and Munson. CI is a soft‐ionization method that produces more intense molecular ions with less fragmentation than electron ionization (EI).
Malvika Dutt +4 more
wiley +1 more source
Rapid Quality Screening of Intra-lot Variability of Acetazolamide Using Near-Infrared Spectrometry. [PDF]
Yoon U +23 more
europepmc +1 more source
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley +1 more source
Subspace Method of Moments for <i>Ab Initio</i> 3-D Single Particle Cryo-EM Reconstruction. [PDF]
Hoskins J +4 more
europepmc +1 more source
Ion Activation Methods for Top‐Down Proteomics
ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley +1 more source
On the Application of a Hybrid Incomplete Exponential Sum to Aperiodic Hamming Correlation of Some Frequency-Hopping Sequences. [PDF]
Li P, Han H.
europepmc +1 more source
First 20 Years of Orbitrap Mass Spectrometry as the Mainstream Analytical Technique
ABSTRACT This review traces the first 20 years of Orbitrap mass spectrometry as a mainstream high‑resolution and accurate‑mass (HR/AM) technology. It outlines the historical development of the Orbitrap analyzer, the evolution of major instrument families, and the key technological innovations that enabled its widespread adoption. Particular emphasis is
Alexander Makarov
wiley +1 more source
Bio-Compositional and Microstructural Changes in Rabbit Knee Collateral Ligaments Eight Weeks After Anterior Cruciate Ligament Transection. [PDF]
Gheisari A +9 more
europepmc +1 more source
Recent Advances in Top‐Down Proteomics for Single‐Cell Research
ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley +1 more source
Exact Solutions of Linear Multiple Delay Partial Differential Equations
ABSTRACT This paper develops an analytical framework for linear differential equations with multiple discrete delays. A new function, referred to as the multiple‐delay exponential function, is introduced, and some of its fundamental properties are established.
Stuart‐James M. Burney
wiley +1 more source

