Results 61 to 70 of about 27,278 (300)

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang, Chengsong Yue, Zhuang Li, Xiaolei Shi, Haoxuan Zhu, Jie Yang, Linyu Li, Jiaxing Song, Shitao Fan, Gaoming Li, Wenzhe Sun, Zhixian Ye, Jiacheng Huang, Dahong Yang, Jinfu Ma, Xu Xu, Zhixi Wang, Lilan Wang, Guojian Liu, Fengli Li, Changwei Guo, Li Qi, Wenjie Zi   +22 more
wiley   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Multiplicative complexity of vector valued Boolean functions [PDF]

, 2018
We consider the multiplicative complexity of Boolean functions with multiple bits of output, studying how large a multiplicative complexity is necessary and sufficient to provide a desired nonlinearity. For so-called ΣΠΣ circuits, we show that there is a
Joan Boyar, Magnus Gausdal Find, Boyar, Joan; id_orcid, Find, Magnus Gausdal   +3 more
core   +1 more source

Sign changes of the partial sums of a random multiplicative function II

Comptes Rendus. Mathématique
We study two models of random multiplicative functions: Rademacher random multiplicative functions supported on the squarefree integers $f$, and Rademacher random completely multiplicative functions $f^*$. We prove that the partial sums $\sum _{n\le x}f^*
Aymone, Marco
doaj   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Multiplicative functionals and entire functions, II [PDF]

Studia Mathematica, 1997
[Part I, cf. Stud. Math. 119, No. 3, 289-297 (1996; Zbl 0868.46037).] The following result is proved in this very interesting paper: Let \(A\) be a complex Banach algebra with a unit \(e\), let \(F\) be a nonconstant entire function, and let \(T\) be a linear functional with \(T(e) = 1\) and such that \(T\circ F\) defined from \(A\) to the complex ...
openaire   +1 more source

Singularities of multiplicative spherical Darboux image and multiplicative rectifying developable surface

Demonstratio Mathematica
In this study, singularity theory is used to explore the geometrical and topological properties of three types of curves and surfaces in multiplicative Euclidean space.
Li Jiaxin, Yao Xinyu, Ma Zikun, Liu Haiming   +3 more
doaj   +1 more source

Partition regularity of Pythagorean pairs

Forum of Mathematics, Pi
We address a core partition regularity problem in Ramsey theory by proving that every finite coloring of the positive integers contains monochromatic Pythagorean pairs (i.e., $x,y\in {\mathbb N}$ such that $x^2\pm y^2=z^2$ for some $z ...
Nikos Frantzikinakis, Oleksiy Klurman, Joel Moreira   +2 more
doaj   +1 more source

Multiple Gamma functions and $L$-functions [PDF]

Mathematical Research Letters, 1996
Multiple gamma functions, first introduced and studied by E. W. Barnes and others around 1900, play an important role in the study of functional equations for Selberg zeta functions and other topics in modern analytic number theory. This paper makes a case for defining a multiple gamma function as a meromorphic function \(\Gamma_P(u)\) associated with ...
openaire   +1 more source