Results 101 to 110 of about 358,667 (342)
Brucella NyxA and NyxB dimerization enhances effector function during infection
FEBS Letters, EarlyView.Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre +4 more
wiley +1 more source
FEBS Letters, EarlyView.UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg +2 more
wiley +1 more source
A note on a nonresonance condition at zero for first-order planar systems
Electronic Journal of Differential Equations, 2015 We introduce a Landesman-Lazer type nonresonance condition at zero for planar systems and discuss its rotational interpretation. We then show an application concerning multiplicity of T-periodic solutions to unforced Hamiltonian systems like $$ Ju'=\
Maurizio Garrione
doaj
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Zdravniški Vestnik, 2007 Background: Health care system in Slovenia has not fully defined all liabilities to cancer patients at the primary, secondary and tertiary levels. No official documents describing precisely the mission of oncology and its tasks to be performed at each ...
Hotimir Lešničar
doaj
Communications in Analysis and MechanicsIn this paper, we studied the existence of multiple normalized solutions to the following Kirchhoff type equation:$ \begin{equation*} \begin{cases} -\left(a\varepsilon^2+b\varepsilon\int_{\mathbb{R}^3}|\nabla u|^2dx\right)\Delta u+V(x)u = \mu u+f(u) &
Yangyu Ni, Jijiang Sun, Jianhua Chen
doaj +1 more source
Common pitfalls in statistical analysis: The perils of multiple testing
Perspectives in Clinical Research, 2016 Multiple testing refers to situations where a dataset is subjected to statistical testing multiple times - either at multiple time-points or through multiple subgroups or for multiple end-points. This amplifies the probability of a false-positive finding.
Priya Ranganathan +2 more
doaj +1 more source
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Insights into the European Years’ Communication Toolboxes
Styles of Communication, 2012 Since 1983 the European syntagm “unity in diversity” has been implemented in the European Years’ communication campaigns. Dependent on subsidiarity and decentralization, European Years focus on a specific issue which constitutes the subject of a year ...
Camelia-Mihaela Cmeciu
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