Results 151 to 160 of about 504,368 (352)
Throughput Rate Optimization in High Multiplicity Sequencing Problems [PDF]
Mixed model assembly systems assemble products (parts) of differenttypes in certain prespecified quantities. A minimal part set is a smallestpossible set of product type quantities, to be called the multiplicities,in which the numbers of assembled ...
Grigoriev,Alexander +1 more
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Eigenvalue multiplicity in triangle-free graphs
, 2016 Let G be a connected triangle-free graph of order n>5 with μ∉{−1,0} as an eigenvalue of multiplicity k>1. We show that if d is the maximum degree in G then k≤n−d−1; moreover, if k=n−d−1 then ...
Rowlinson, Peter
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Who Is the Customer? On Multiple-Customer Representation in Supply Chains
LogisticsBackground: Customer orders are key in developing logistics processes and in strategic developments of customer orientation. This paper investigates the notion of customer orientation.
Benedikte Borgström +2 more
doaj +1 more source
Sign Systems Studies, 2016 This article interprets Jakob von Uexküll’s understanding of different beings’ Innenwelt, Gegenwelt, and umwelt through Deleuzian insights of multiplicity, context, and particularity. This Deleuzian interpolation into Uexküll’s insights acknowledges the absence of a unitary ‘human’ view of nature, recognizing instead that plural viewpoints of cultures,
openaire +4 more sources
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Positive Solutions to a System of Coupled Hadamard Fractional Boundary Value Problems
Fractal and FractionalWe explore the existence, uniqueness, and multiplicity of positive solutions to a system of Hadamard fractional differential equations that contain fractional integral terms.
Alexandru Tudorache, Rodica Luca
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
, 2013 The average transverse momentum ⟨pT⟩ versus the charged-particle multiplicity Nch was measured in p-Pb collisions at a collision energy per nucleon-nucleon pair √sNN = 5.02 TeV and in pp collisions at collision energies of s√=0.9, 2.76, and 7 TeV in the ...
안상언 +3 more
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