Results 41 to 50 of about 316,257 (289)
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Fast Proximal Linearized Alternating Direction Method of Multiplier with Parallel Splitting
The Augmented Lagragian Method (ALM) and Alternating Direction Method of Multiplier (ADMM) have been powerful optimization methods for general convex programming subject to linear constraint.
Li, Huan +3 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
In this paper, we consider the wave equation with a weak internal constant delay term: $$ u''(x, t)-\Delta_{x}u(x, t)+ \mu_1(t) \ u'(x, t) + \mu_2(t) \ u'(x, t-\tau) = 0 $$ in a bounded domain.
Abbes Benaissa +2 more
doaj +1 more source
Distributed Alternating Direction Method of Multipliers [PDF]
We consider a network of agents that are cooperatively solving a global unconstrained optimization problem, where the objective function is the sum of privately known local objective functions of the agents. Recent literature on distributed optimization methods for solving this problem focused on subgradient based methods, which typically converge at ...
Wei, Ermin, Ozdaglar, Asuman E.
openaire +3 more sources
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Computer program for fitting low-order polynomial splines by method of least squares [PDF]
FITLOS is computer program which implements new curve fitting technique. Main program reads input data, calls appropriate subroutines for curve fitting, calculates statistical analysis, and writes output data.
Smith, P. J.
core +1 more source
Characterizations of GEM detector prototype
At NISER-IoP detector laboratory an initiative is taken to build and test Gas Electron Multiplier (GEM) detectors for ALICE experiment. The optimisation of the gas flow rate and the long-term stability test of the GEM detector are performed.
Bhattacharya, P. +9 more
core +3 more sources
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
Variable Support Control for the Wave Equation: A Multiplier Approach
We study the controllability of the multidimensional wave equation in a bounded domain with Dirichlet boundary condition, in which the support of the control is allowed to change over time.
Agresti, Antonio +2 more
core +1 more source

