Results 41 to 50 of about 314,654 (293)

Photocathodes for a post-processed imaging array [PDF]

open access: yes, 2009
Preliminary results of a photon detector combining a Micromegas like multiplier coated with a UV-sensitive CsI photocathode are described. The multiplier is made in the CMOS compatible InGrid technology, which allows to post-process it directly on the ...
Breskin, Amos   +8 more
core   +1 more source

Variable Support Control for the Wave Equation: A Multiplier Approach

open access: yes, 2018
We study the controllability of the multidimensional wave equation in a bounded domain with Dirichlet boundary condition, in which the support of the control is allowed to change over time.
Agresti, Antonio   +2 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Energy decay of solutions for a wave equation with a constant weak delay and a weak internal feedback

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2014
In this paper, we consider the wave equation with a weak internal constant delay term: $$ u''(x, t)-\Delta_{x}u(x, t)+ \mu_1(t) \ u'(x, t) + \mu_2(t) \ u'(x, t-\tau) = 0 $$ in a bounded domain.
Abbes Benaissa   +2 more
doaj   +1 more source

Computer program for fitting low-order polynomial splines by method of least squares [PDF]

open access: yes, 1972
FITLOS is computer program which implements new curve fitting technique. Main program reads input data, calls appropriate subroutines for curve fitting, calculates statistical analysis, and writes output data.
Smith, P. J.
core   +1 more source

Fast Proximal Linearized Alternating Direction Method of Multiplier with Parallel Splitting

open access: yes, 2015
The Augmented Lagragian Method (ALM) and Alternating Direction Method of Multiplier (ADMM) have been powerful optimization methods for general convex programming subject to linear constraint.
Li, Huan   +3 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

The Influence of the Basic Parameters of the Numerical Model on the Contact Pressure in Dynamic Tasks [PDF]

open access: yesTransactions of the VŠB-Technical University of Ostrava, Mechanical Series, 2013
The paper is devoted to quasi-static and low-velocity impact simulation using finite element modelling. The paper describes the effects of contact models, contact parameters, integration method, and the velocity of impact on contact stresses values ...
Irina SEMENOVA, Petr HORYL
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

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