Results 71 to 80 of about 314,654 (293)

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

MANFAAT INVESTASI PEMBANGUNAN JALAN TOL BANDUNG INTRA URBAN DARI PERSPEKTIF MAKRO

Tataloka, 2016
This article aims to assess the economic impact in a wider perspectives of the Bandung Intra Urban toll road project. Bandung Intra Urban Toll Road is a proposed project aimed at connecting the east and west corridor along the 27.273 km of Bandung.
P Pradono, Handini Pradhitasari
doaj   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon, Dana Olofson, Diana Anissian, Divyanshu Dubey, Eoin P. Flanagan, Max C. Herman, Sarosh R. Irani, Daniel H. Lachance, Maria A. Willrich, Sean Pittock, John R. Mills, Anastasia Zekeridou   +11 more
wiley   +1 more source

Conserved Vectors, Analytic Solutions and Numerical Simulation of Soliton Collisions of the Modified Gardner Equation

AppliedMath
This paper aims to study the modified Gardner (mG) equation that was proposed in the literature a short while ago. We first construct conserved vectors of the mG equation by invoking three different techniques; namely the method of multiplier, Noether’s ...
Chaudry Masood Khalique, Carel Olivier, Boikanyo Pretty Sebogodi   +2 more
doaj   +1 more source

On the construction of Nadel multiplier ideal sheaves and the limiting behavior of the Ricci flow

, 2007
In this note we construct Nadel multiplier ideal sheaves using the Ricci flow on Fano manifolds. This extends a result of Phong, Sesum and Sturm. These sheaves, like their counterparts constructed by Nadel for the continuity method, can be used to obtain
Rubinstein, Yanir A.
core   +4 more sources

Comprehensive Assessment of Arterial, Tissue, and Venous Collaterals for Evaluating the Infarct Growth Rate: The Multimodal Collateral Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto, Umberto Pensato, Ilaria Casetta, Giorgio U. Marcello, Angelo Barra, Anna Poggesi, Edoardo Carlesi, Sara Mancini, Andrea Ginestroni, Vittorio Miele, Alessandro Padovani, Andrea Morotti, Enrico Fainardi   +12 more
wiley   +1 more source

A Kolmogorov-Smirnov Type Test for Positive Quadrant Dependence [PDF]

We consider a consistent test, that is similar to a Kolmogorov-Smirnov test, of the complete set of restrictions that relate to the copula representation of positive quadrant dependence.
Olivier Scaillet
core  

Validation of a Genetic Risk Score Combined With Clinical Variables for Predicting Pulmonary Fibrosis in Early Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective Pulmonary fibrosis (PF) is a severe extra‐articular manifestation of rheumatoid arthritis (RA). This study aimed to externally validate a genetic risk score (GRS) and a combined risk score (CRS) for predicting the risk of RA‐associated PF in an independent cohort of patients with early RA.
Mikael Brink, Austin Wheeler, Bryant R. England, Solbritt Rantapää‐Dahlqvist   +3 more
wiley   +1 more source

Energy decay for elastic wave equations with critical damping

Electronic Journal of Differential Equations, 2014
We show that the total energy decays at the rate $E_u(t) = O(t^{-2})$, as $t \to +\infty$, for solutions to the Cauchy problem of a linear system of elastic wave with a variable damping term.
Jaqueline Luiza Horbach, Naoki Nakabayashi   +1 more
doaj